[HTML][HTML] Patterns of cannabis and alcohol co-use: Substitution versus complementary effects
PURPOSE The purpose of this review is to discuss the literature regarding the concurrent
use (co-use) of alcohol and cannabis and competing hypotheses as to whether cannabis …
use (co-use) of alcohol and cannabis and competing hypotheses as to whether cannabis …
State-of-the-art behavioral and pharmacological treatments for alcohol use disorder
Background: Alcohol use disorder (AUD) and its associated consequences remain
significant public health concerns. Given that AUD represents a spectrum of severity …
significant public health concerns. Given that AUD represents a spectrum of severity …
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies
Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR)
antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may …
antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may …
Ibudilast, a neuroimmune modulator, reduces heavy drinking and alcohol cue-elicited neural activation: a randomized trial
Ibudilast, a neuroimmune modulator which selectively inhibits phosphodiesterases (PDE)-3,-
4,-10, and-11, and macrophage migration inhibitory factor (MIF), shows promise as a novel …
4,-10, and-11, and macrophage migration inhibitory factor (MIF), shows promise as a novel …
Translational opportunities in animal and human models to study alcohol use disorder
Animal and human laboratory paradigms offer invaluable approaches to study the complex
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …
Evidence for incentive salience sensitization as a pathway to alcohol use disorder
The incentive salience sensitization (ISS) theory of addiction holds that addictive behavior
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …
Understanding low treatment seeking rates for alcohol use disorder: a narrative review of the literature and opportunities for improvement
Despite a well-documented global burden of disease attributable to alcohol use disorder
(AUD), treatment seeking rates remain low. In this qualitative literature review, we address …
(AUD), treatment seeking rates remain low. In this qualitative literature review, we address …
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
P Sampedro-Piquero, DL de Guevara-Miranda… - Neuroscience & …, 2019 - Elsevier
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …
The Addictions Neuroclinical Assessment negative emotionality domain among treatment‐seekers with alcohol use disorder: Construct validity and measurement …
VR Votaw, MR Pearson, E Stein… - Alcoholism: Clinical …, 2020 - Wiley Online Library
Background The Addictions Neuroclinical Assessment (ANA), a framework for measuring
heterogeneity in alcohol use disorder (AUD), focuses on 3 domains that reflect …
heterogeneity in alcohol use disorder (AUD), focuses on 3 domains that reflect …
Ibudilast attenuates alcohol cue–elicited frontostriatal functional connectivity in alcohol use disorder
Background Ibudilast, a novel neuroimmune modulator being studied to treat alcohol use
disorder (AUD), was shown in a randomized controlled trial (NCT03489850) to reduce …
disorder (AUD), was shown in a randomized controlled trial (NCT03489850) to reduce …