The crossroads: divergent roles of virus‐specific CD4+ T lymphocytes in determining the outcome for human papillomavirus infection

D van Bockel, A Kelleher - Immunology and Cell Biology, 2023 - Wiley Online Library
Despite the widespread availability of effective prophylactic vaccines to prevent human
papillomavirus (HPV) infection, HPV remains a major health burden. For health care …

HPV-transgenic mouse models: Tools for studying the cancer-associated immune response

C Santos, M Vilanova, R Medeiros, RMG da Costa - Virus research, 2017 - Elsevier
For decades, research on the pathogenesis of papillomavirus-induced lesions, particularly
of human papillomavirus (HPV) has relied on the use of animal models. Among these, HPV …

How enhancing immunity to low‐risk HPV could cure recurrent respiratory papillomatosis

K Bai, C Allen - The Laryngoscope, 2021 - Wiley Online Library
Recurrent respiratory papillomatosis (RRP) is currently treated with repeat surgical resection
of papillomatous disease that does not address the fundamental underlying issue of chronic …

Aggressive recurrent respiratory papillomatosis: A series of five consecutive patients successfully treated with adjuvant intravenous bevacizumab. A single Belgian …

F Collette, G Lawson, S Hassid, G Delahaut… - Head & …, 2023 - Wiley Online Library
Background Recurrent respiratory papillomatosis (RRP) is a currently incurable benign
neoplasm caused by human papilloma virus (HPV) infection. It usually reduces voice …

[HTML][HTML] Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions

ZK Tuong, K Noske, P Kuo, AA Bashaw, SM Teoh… - Papillomavirus …, 2018 - Elsevier
Currently available vaccines prevent HPV infection and development of HPV-associated
malignancies, but do not cure existing HPV infections and dysplastic lesions. Persistence of …

Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation

OL Cherkashina, EI Morgun, AL Rippa… - International Journal of …, 2023 - mdpi.com
Most of the knowledge about human skin homeostasis, development, wound healing, and
diseases has been accumulated from human skin biopsy analysis by transferring from …

Patient-derived organotypic epithelial rafts model phenotypes in juvenile-onset recurrent respiratory papillomatosis

MC Bedard, MG Brusadelli, A Carlile, S Ruiz-Torres… - Viruses, 2021 - mdpi.com
Juvenile-onset recurrent respiratory papillomatosis (JoRRP) is driven by human
papillomavirus (HPV) low-risk strains and is associated with significant morbidity. While …

Preclinical models of laryngeal papillomavirus infection: a scoping review

RE King, A Bilger, J Rademacher… - The …, 2023 - Wiley Online Library
Objective Laryngeal human papillomavirus (HPV) infection causes recurrent respiratory
papillomatosis (RRP) and accounts for up to 25% of laryngeal cancers. Lack of satisfactory …

HPV strain predicts severity of juvenile-onset recurrent respiratory papillomatosis with implications for disease screening

MC Bedard, A de Alarcon, YF Kou, D Lee, A Sestito… - Cancers, 2021 - mdpi.com
Simple Summary Although it is known that low-risk HPV causes juvenile-onset recurrent
respiratory papillomatosis (JoRRP), viral factors such as HPV strain are not routinely …

Biologics for the treatment of recurrent respiratory papillomatosis

CT Allen - Otolaryngologic Clinics of North America, 2021 - oto.theclinics.com
Recurrent respiratory papillomatosis (RRP) is a neoplastic disorder that manifests as
papillomatous growths in the upper aerodigestive tract. The symptom profile, socioeconomic …