Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications

AZ Mirza, II Althagafi, H Shamshad - European journal of medicinal …, 2019 - Elsevier
The peroxisome proliferator-activated receptors (PPAR-α, PPAR-β/δ, and PPAR-γ) are
members of the nuclear receptor super-family, acting as ligand-inducible transcription …

Benzothiazole derivatives as anticancer agents

A Irfan, F Batool, SA Zahra Naqvi, A Islam… - Journal of enzyme …, 2020 - Taylor & Francis
Benzothiazole (BTA) belongs to the heterocyclic class of bicyclic compounds. BTA
derivatives possesses broad spectrum biological activities such as anticancer, antioxidant …

A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

RS Keri, MR Patil, SA Patil, S Budagumpi - European Journal of Medicinal …, 2015 - Elsevier
Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update

K Laxmikeshav, P Kumari… - Medicinal Research …, 2022 - Wiley Online Library
This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Biological aspects of emerging benzothiazoles: a short review

R Ali, N Siddiqui - Journal of chemistry, 2013 - Wiley Online Library
In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …

[HTML][HTML] Thiazole ring-the antimicrobial, anti-inflammatory, and anticancer active scaffold

S Hosseininezhad, A Ramazani - Arabian Journal of Chemistry, 2023 - Elsevier
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …

New horizons in benzothiazole scaffold for cancer therapy: Advances in bioactivity, functionality, and chemistry

PC Sharma, D Sharma, A Sharma, KK Bansal… - Applied Materials …, 2020 - Elsevier
In the pasture of oncology, anticancer agents having advanced modes of action are of great
interest because of increasing chronicity of resistance against anticancer drugs. Heterocyclic …

A mini-review on pharmacological importance of benzothiazole scaffold

M Asif, M Imran - Mini-Reviews in Organic Chemistry, 2021 - ingentaconnect.com
Heterocyclic compounds are important because they have almost all types of
pharmacological properties. Due to these properties of heterocyclic compounds, they …

N-alkylation of substituted 2-amino benzothiazoles by 1, 4-bis (bromo methyl) benzene on mixed oxides at room temperature and study their biological activity

WM Al-Joboury, KA Al-Badrany, NJ Asli - AIP Conference Proceedings, 2022 - pubs.aip.org
In this work, substituted 2-amino benzothiazoles (W1-4) were synthesized from, the reaction
of aniline substituted with potassium thiocyanate in presence of broomin. The selective …

Advancement in the development of heterocyclic nucleosides for the treatment of cancer-A review

AZ Mirza - Nucleosides, Nucleotides and Nucleic Acids, 2019 - Taylor & Francis
Cancer diseases are widely recognised as an important medical problem and killing millions
of people in a year. Chemotherapeutic drugs are successful against cancer in many cases …