Sex differences in the epilepsies and associated comorbidities: implications for use and development of pharmacotherapies
The epilepsies are common neurologic disorders characterized by spontaneous recurrent
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …
Mechanisms linking neurological disorders with reproductive endocrine dysfunction: insights from epilepsy research
CA Cutia, CA Christian-Hinman - Frontiers in Neuroendocrinology, 2023 - Elsevier
Gonadal hormone actions in the brain can both worsen and alleviate symptoms of
neurological disorders. Although neurological conditions and reproductive endocrine …
neurological disorders. Although neurological conditions and reproductive endocrine …
Sex-specific disease modifiers in juvenile myoclonic epilepsy
A Shakeshaft, N Panjwani, A Collingwood… - Scientific reports, 2022 - nature.com
Juvenile myoclonic epilepsy (JME) is a common idiopathic generalised epilepsy with
variable seizure prognosis and sex differences in disease presentation. Here, we investigate …
variable seizure prognosis and sex differences in disease presentation. Here, we investigate …
Hormones and sex-specific medicine in human physiopathology
MR Tokatli, LG Sisti, E Marziali, L Nachira, MF Rossi… - Biomolecules, 2022 - mdpi.com
A prodigious increment of scientific evidence in both preclinical and clinical studies is
narrowing a major gap in knowledge regarding sex-specific biological responses observed …
narrowing a major gap in knowledge regarding sex-specific biological responses observed …
Protective effects of intranasally administrated oxytocin-loaded nanoparticles on pentylenetetrazole-kindling epilepsy in terms of seizure severity, memory …
Pentylenetetrazole (PTZ)-induced kindling is an animal model for studying human temporal
lobe epilepsy (TLE), which is characterized by alterations of hippocampal neurons and …
lobe epilepsy (TLE), which is characterized by alterations of hippocampal neurons and …
Alterations in salivary biochemical composition and redox state disruption induced by the anticonvulsant valproic acid in male rat salivary glands
RN de Freitas, LGL da Silva, GA Fiais… - Archives of Oral …, 2023 - Elsevier
Objective To investigate the effects of the anticonvulsant valproic acid (VPA) on salivary
glands in male rat using biochemical, functional, histomorphometric, and redox state …
glands in male rat using biochemical, functional, histomorphometric, and redox state …
Differences in evolution of epileptic seizures and topographical distribution of tissue damage in selected limbic structures between male and female rats submitted to …
D Matovu, EA Cavalheiro - Frontiers in Neurology, 2022 - frontiersin.org
Epidemiological evidence shows that clinical features and comorbidities in temporal lobe
epilepsy (TLE) may have different manifestations depending on the sex of patients …
epilepsy (TLE) may have different manifestations depending on the sex of patients …
Health related quality of life in a Saudi population of patients with epilepsy
A Eskandrani, E Almusallam, A Alenizi, S Asiri… - Neurosciences …, 2023 - nsj.org.sa
Objectives: To assess the quality of life for epilepsy patients in Saudi Arabia. Epilepsy, one
of the most prevalent chronic neurological conditions in the world, frequently results in a low …
of the most prevalent chronic neurological conditions in the world, frequently results in a low …
Sex‐specific differences in mortality and neurocardiac interactions in the Kv1. 1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)
K Paulhus, P Kumar, K Kneale… - The Journal of …, 2025 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a devastating complication of epilepsy
with possible sex‐specific risk factors, although the exact relationship between sex and …
with possible sex‐specific risk factors, although the exact relationship between sex and …
Considering social determinants of health in the relationship between physical activity and exercise engagement and cognitive impairment among persons with …
B Hansen, JB Allendorfer - Frontiers in Rehabilitation Sciences, 2022 - frontiersin.org
Many persons with epilepsy (PWE) are not as active or physically fit as compared to the
general population. This lack of engagement in physical activity has been attributed to a …
general population. This lack of engagement in physical activity has been attributed to a …