Antimicrobial resistance was one of the top priorities for global public health before the start
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …

Here we have outlined the recent (2011–2022) developments in the synthesis of modified
indomethacin-based analogues for the selective inhibition of COX-2 and then highlighted …

A new series of pyrimidine-5-carbonitrile derivatives 8a-p carrying the 1, 3-thiazole moiety
has been designed and synthesized as novel anti-inflammatory EGFR inhibitors with cardiac …

Abstract Two new series of 1, 3, 4-oxadiazole and coumarin derivatives based on pyrimidine-
5-carbonitrile scaffold have been synthesized and evaluated for their COX-1/COX-2 …

Background Heterocyclic pyrimidine nucleus, which is an essential base component of the
genetic material of deoxyribonucleic acid, demonstrated various biological activities. A …

Antibiotic resistance is a problem that continues to challenge the healthcare sector,
especially in clinically significant pathogens like methicillin-resistant Staphylococcus aureus …

Recently, nanotechnology has achieved tremendous recognition in science owing to its
outstandingly productive uses. 1 Some metallic nanoparticles (NPs) are limited in their use …

Dihydropyrimidine derivatives are the most important scaffolds due to structural similarities
with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a …

Abstract Objectives Dalbergia sissoo Roxb. ex DC is an important medicinal plant native to
tropical and sub-tropical areas belonging to Fabaceae family of genus Dalbergia commonly …

The present chapter will focus on the recent advances in the design and development of
environmentally sustainable organic transformations involving the use of deep eutectic …