[HTML][HTML] Biginelli reaction mediated synthesis of antimicrobial pyrimidine derivatives and their therapeutic properties
M Marinescu - Molecules, 2021 - mdpi.com
Antimicrobial resistance was one of the top priorities for global public health before the start
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …
The indole nucleus as a selective COX-2 inhibitor and anti-inflammatory agent (2011–2022)
Here we have outlined the recent (2011–2022) developments in the synthesis of modified
indomethacin-based analogues for the selective inhibition of COX-2 and then highlighted …
indomethacin-based analogues for the selective inhibition of COX-2 and then highlighted …
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1, 3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with …
A new series of pyrimidine-5-carbonitrile derivatives 8a-p carrying the 1, 3-thiazole moiety
has been designed and synthesized as novel anti-inflammatory EGFR inhibitors with cardiac …
has been designed and synthesized as novel anti-inflammatory EGFR inhibitors with cardiac …
Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies
Abstract Two new series of 1, 3, 4-oxadiazole and coumarin derivatives based on pyrimidine-
5-carbonitrile scaffold have been synthesized and evaluated for their COX-1/COX-2 …
5-carbonitrile scaffold have been synthesized and evaluated for their COX-1/COX-2 …
[HTML][HTML] Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
Background Heterocyclic pyrimidine nucleus, which is an essential base component of the
genetic material of deoxyribonucleic acid, demonstrated various biological activities. A …
genetic material of deoxyribonucleic acid, demonstrated various biological activities. A …
[HTML][HTML] Bioactive 2-(Methyldithio)Pyridine-3-Carbonitrile from Persian Shallot (Allium stipitatum Regel.) Exerts Broad-Spectrum Antimicrobial Activity
A Karunanidhi, E Ghaznavi-Rad, J Jeevajothi Nathan… - Molecules, 2019 - mdpi.com
Antibiotic resistance is a problem that continues to challenge the healthcare sector,
especially in clinically significant pathogens like methicillin-resistant Staphylococcus aureus …
especially in clinically significant pathogens like methicillin-resistant Staphylococcus aureus …
Green Synthesis of Copper Oxide Nanoparticles with an Extract of Euphorbia maculata and Their Use in the Biginelli Reaction
H Alinezhad, K Pakzad - Organic Preparations and Procedures …, 2020 - Taylor & Francis
Recently, nanotechnology has achieved tremendous recognition in science owing to its
outstandingly productive uses. 1 Some metallic nanoparticles (NPs) are limited in their use …
outstandingly productive uses. 1 Some metallic nanoparticles (NPs) are limited in their use …
An Overview of Synthesis and Biological Activity of Dihydropyrimidine Derivatives.
AC Dudhe, R Dudhe, O Porwal… - Mini Reviews in Medicinal …, 2022 - europepmc.org
Dihydropyrimidine derivatives are the most important scaffolds due to structural similarities
with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a …
with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a …
Phytochemistry and pharmacology of Dalbergia sissoo Roxb. ex DC: a review
M Bajpai - Journal of Pharmacy and Pharmacology, 2023 - academic.oup.com
Abstract Objectives Dalbergia sissoo Roxb. ex DC is an important medicinal plant native to
tropical and sub-tropical areas belonging to Fabaceae family of genus Dalbergia commonly …
tropical and sub-tropical areas belonging to Fabaceae family of genus Dalbergia commonly …
Use of sustainable organic transformations in the construction of heterocyclic scaffolds
S Khandelwal, YK Tailor, E Rushell, M Kumar - Green Approaches in …, 2020 - Elsevier
The present chapter will focus on the recent advances in the design and development of
environmentally sustainable organic transformations involving the use of deep eutectic …
environmentally sustainable organic transformations involving the use of deep eutectic …