Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …

JL Wolfender, JM Nuzillard, JJJ Van Der Hooft… - Analytical …, 2018 - ACS Publications
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides

PK Agrawal - Phytochemistry, 1992 - Elsevier
The potential of one-and two-dimensional NMR techniques for the identification of individual
sugar residues, their anomeric configuration, interglycosidic linkages, sequencing and the …

A marine microbiome antifungal targets urgent-threat drug-resistant fungi

F Zhang, M Zhao, DR Braun, SS Ericksen… - Science, 2020 - science.org
New antifungal drugs are urgently needed to address the emergence and transcontinental
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …

[HTML][HTML] Pure shift NMR

K Zangger - Progress in nuclear magnetic resonance spectroscopy, 2015 - Elsevier
Although scalar-coupling provides important structural information, the resulting signal
splittings significantly reduce the resolution of NMR spectra. Limited resolution is a particular …

[PDF][PDF] MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

AD Bax, DG Davis - Journal of Magnetic Resonance (1969), 1985 - Citeseer
Recently, we have shown that net magnetization transfer among scalar coupled
homonuclear spins can be obtained by the application of a spin-lock field (I), or more …

13C NMR spectra of pentacyclic triterpenoids—a compilation and some salient features

SB Mahato, AP Kundu - Phytochemistry, 1994 - Elsevier
13C NMR Spectra of pentacyclic triterpenoids—a compilation and some salient features -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

S Grzesiek, A Bax - Journal of the American Chemical Society, 1992 - ACS Publications
Conclusions Analogs of deglyco BLM, each of which lack one of the thiazole rings present in
the parent molecule, were found to form Fe complexes that activatedoxygen as well as BLM …

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

GR Pettit, Y Kamano, CL Herald… - Journal of the …, 1987 - ACS Publications
= Ph), when hydrolyzed under the above conditions, afforded a quantitative yield of (25)-
azidophenylacetic acid (6d)(R= Ph) having a minimum enantiomeric purity of 99.5%. In the …

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

D Marion, K Wüthrich - Biochemical and biophysical research …, 1983 - Elsevier
Two-dimensional correlated spectroscopy (COSY) is used for measurements of proton-
proton spin-spin coupling constants in protein 1 H NMR spectra. High digital resolution …

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

M Rance, OW Sørensen, G Bodenhausen… - Biochemical and …, 1983 - Elsevier
A double quantum filter is inserted into a two-dimensional correlated (COSY) 1 H NMR
experiment to obtain phase-sensitive spectra in which both cross peak and diagonal peak …