Therapeutic effect of decellularized extracellular matrix-based hydrogel for radiation esophagitis by 3D printed esophageal stent

DH Ha, S Chae, JY Lee, JY Kim, J Yoon, T Sen… - Biomaterials, 2021 - Elsevier
Radiation esophagitis, the most common acute adverse effect of radiation therapy, leads to
unwanted consequences including discomfort, pain, an even death. However, no direct cure …

Therapeutic effect of dental pulp stem cell transplantation on a rat model of radioactivity-induced esophageal injury

C Zhang, Y Zhang, Z Feng, F Zhang, Z Liu, X Sun… - Cell Death & …, 2018 - nature.com
Dental pulp stem cell (DPSC) transplantation has been demonstrated to promote the
regeneration and repair of tissues and organs and is a potentially effective treatment for …

Metabolic profiling implicates a critical role of cyclooxygenase-2-mediated arachidonic acid metabolism in radiation-induced esophageal injury in rats

W Tu, Y Feng, Q Lai, J Wang, W Yuan… - Radiation …, 2022 - meridian.allenpress.com
Radiation-induced esophageal injury (RIEI) is a major dose-limiting complication of
radiotherapy, especially for esophageal and thoracic cancers. RIEI is a multi-factorial and …

Predictive modeling of thoracic radiotherapy toxicity and the potential role of serum alpha-2-macroglobulin

D Von Reibnitz, ED Yorke, JH Oh, AP Apte… - Frontiers in …, 2020 - frontiersin.org
Background: To investigate the impact of alpha-2-macroglobulin (A2M), a suspected intrinsic
radioprotectant, on radiation pneumonitis and esophagitis using multifactorial predictive …

Construction of an immune-related lncRNA-miRNA-mRNA regulatory network in radiation-induced esophageal injury in rats

F Wu, X Zhang, S Zhang, Y Zhang, Y Feng… - International …, 2023 - Elsevier
Radiation-induced esophageal injury (RIEI) is an adverse reaction of radiation therapy in
patients with esophageal cancer, lung cancer and other malignant tumors. Competitive …

Transcriptome profiling unveils a critical role of IL-17 signaling-mediated inflammation in radiation-induced esophageal injury in rats

J Yao, J Zhang, J Wang, Q Lai, W Yuan… - Dose …, 2022 - journals.sagepub.com
Elucidation of the molecular mechanisms involving the initiation and progression of radiation-
induced esophageal injury (RIEI) is important for prevention and treatment. Despite ongoing …

An RNA-seq-based expression profiling of radiation-induced esophageal injury in a rat model

Z Sun, J Li, M Lin, S Zhang, J Luo, Y Tang - Dose-Response, 2019 - journals.sagepub.com
Radiation-induced acute injury is the main reason for the suspension of radiotherapy and
unsuccessful treatment of cancer. It is of great importance to understand the molecular …

Serum Alpha-2-Macroglobulin as an intrinsic radioprotective factor in patients undergoing thoracic radiation therapy

D von Reibnitz, ED Yorke, JH Oh, AP Apte, J Yang… - BioRxiv, 2019 - biorxiv.org
Objective To investigate the impact of alpha-2-macroglobulin (A2M), a suspected intrinsic
radioprotectant, on radiation pneumonitis and esophagitis. Additionally, we establish …

[HTML][HTML] Current status of evaluation techniques for radiation esophagitis induced by tumor radiotherapy

J DONG, J CHENG, C WANG, H LIU - xdzlyx.com
Tumor radiotherapy has entered the era of precision radiotherapy. With the rapid
development of molecular biology technology, the use of biomarkers to evaluate the adverse …

The old and the new: mouse models for evaluating the therapeutic margin of radiation in lung cancer

L Lourenco - 2017 - ora.ox.ac.uk
Background: Radiotherapy is widely used in the treatment of lung cancer, with both curative
and palliative intent according to the stage of the disease. The tumour control potential of …