Epithelial barriers in allergy and asthma

PW Hellings, B Steelant - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Epidemiology of chronic rhinosinusitis: prevalence and risk factors

AR Sedaghat, EC Kuan, GK Scadding - The Journal of Allergy and Clinical …, 2022 - Elsevier
Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

Biologics for chronic rhinosinusitis—A modern option for therapy

R Cergan, ON Berghi, M Dumitru, D Vrinceanu… - Life, 2023 - mdpi.com
Chronic rhinosinusitis (CRS) is an important ENT pathology which affects about 5–12% of
the general population. The treatment of CRS can be pharmacological (nasal sprays …

Survey on use of local and systemic corticosteroids in the management of chronic rhinosinusitis with nasal polyps: identification of unmet clinical needs

E De Corso, C Pipolo, E Cantone, G Ottaviano… - Journal of Personalized …, 2022 - mdpi.com
Background: Local and systemic corticosteroids have long been the workhorse in
management of chronic rhinosinusitis with nasal polyps (CRSwNP), although there is no …

Eosinophils—from cradle to grave: An EAACI task force paper on new molecular insights and clinical functions of eosinophils and the clinical effects of targeted …

M Jesenak, Z Diamant, D Simon, E Tufvesson… - Allergy, 2023 - Wiley Online Library
Over the past years, eosinophils have become a focus of scientific interest, especially in the
context of their recently uncovered functions (eg antiviral, anti‐inflammatory, regulatory) …

Effect of an intranasal corticosteroid on quality of life and local microbiome in young children with chronic rhinosinusitis: a randomized clinical trial

M Latek, P Łacwik, K Molińska, A Błauż, J Lach… - JAMA …, 2023 - jamanetwork.com
Importance Intranasal corticosteroids (INCs) remain the first-line treatment of chronic
rhinosinusitis (CRS) in both adults and children, despite the lack of evidence regarding their …

Biocompatible materials in otorhinolaryngology and their antibacterial properties

J Spałek, P Ociepa, P Deptuła, E Piktel… - International Journal of …, 2022 - mdpi.com
For decades, biomaterials have been commonly used in medicine for the replacement of
human body tissue, precise drug-delivery systems, or as parts of medical devices that are …

Asthma and chronic rhinosinusitis: how similar are they in pathogenesis and treatment responses?

A Matucci, S Bormioli, F Nencini, F Chiccoli… - International Journal of …, 2021 - mdpi.com
Severe asthma and rhinosinusitis represent frequent comorbidities, complicating the overall
management of the disease. Both asthma and chronic rhinosinusitis (CRS) can be …

Environmental air pollution and chronic rhinosinusitis: A systematic review

EM Leland, V Vohra, SM Seal, Z Zhang… - Laryngoscope …, 2022 - Wiley Online Library
Objective Chronic rhinosinusitis (CRS) is a highly prevalent and burdensome disease. The
pathophysiology is not fully elucidated, but environmental pollutants have been suggested …

Taste and smell disorders in cancer treatment: results from an integrative rapid systematic review

T Buttiron Webber, IM Briata, A DeCensi… - International Journal of …, 2023 - mdpi.com
Taste and smell disorders (TSDs) are common side effects in patients undergoing cancer
treatments. Knowing which treatments specifically cause them is crucial to improve patients' …