Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Ageing, cellular senescence and chronic kidney disease: expe... : Current Opinion in Nephrology
and Hypertension Ageing, cellular senescence and chronic kidney disease: experimental …

Mechanistic target of rapamycin complex 1 (mTORC1) is a multi-protein complex widely
found in eukaryotes. It serves as a central signaling node to coordinate cell growth and …

Correlation between objects is prone to occur coincidentally, and exploring correlation or
association in most situations does not answer scientific questions rich in causality. Causal …

Abstract Human Positive Coactivator 4 (PC4) is a multifaceted chromatin protein involved in
diverse cellular processes including genome organization, transcription regulation …

Skeletal muscle adaptation to exercise involves various phenotypic changes that enhance
the metabolic and contractile functions. One key regulator of these adaptive responses is the …

Owing to its constant exposure to the external environment and various stimuli, skin ranks
among the organs most vulnerable to manifestations of aging. Preventing and delaying skin …

Bladder cancer is a common malignancy with a poor prognosis worldwide. Positive cofactor
4 (PC4) is widely reported to promote malignant phenotypes in various tumors. Nonetheless …

Background and aims Human positive cofactor 4 (PC4) is associated with the development
and therapeutic resistance of several malignancies. However, the role of PC4 in …

Correlation between objects does not answer many scientific questions because of the lack
of causal but the excess of spurious information and is prone to happen by coincidence …