Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …

A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed …

Aging is a natural biological event that has some downsides such as increased frailty,
decline in cognitive and physical functions leading to chronical diseases, and lower quality …

Aims/hypothesis We aimed to evaluate associations of multiple recommended dietary
patterns (ie the alternate Mediterranean diet [aMED], the Healthy Eating Index [HEI]-2015 …

Polyamine metabolites provide pathophysiological information on disease or therapeutic
efficacy, yet rapid screening methods for these biomarkers are lacking. Here, we developed …

Introduction: Trimethylamine N-oxide (TMAO) may play a key mediator role in the
relationship between the diet, gut microbiota and cardiovascular diseases, particularly in …

The extent to which variation in food-related metabolites are attributable to non-dietary
factors remains unclear, which may explain inconsistent food-metabolite associations …

Proline betaine (Pro-B) has been identified as a biomarker of dietary citrus intake, yet gaps
remain in its validation as a quantitative predictor of intake during various physiological …

Abstract Background Black Americans suffer disparities in risk for cardiometabolic and other
chronic diseases. Findings from the Adventist Health Study-2 (AHS-2) cohort have shown …

A mother's intrauterine environment influences her health and that of her offspring, at birth
and in the future. Herein, we present an overview of our Canadian Institutes of Health …