A review on biological activities of Schiff base, hydrazone, and oxime derivatives of curcumin
S Omidi, A Kakanejadifard - RSC advances, 2020 - pubs.rsc.org
Curcumin (1, 7-bis [4-hydroxy-3-methoxyphenyl]-1, 6-heptadiene-3, 5-dione) is the main
pigment present in the turmeric rhizome and shows various biological properties. The …
pigment present in the turmeric rhizome and shows various biological properties. The …
Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies
GC Arya, K Kaur, V Jaitak - European journal of medicinal chemistry, 2021 - Elsevier
Breast cancer is the second most leading cause of death among women. Multiple drugs
have been approved by FDA for the treatment of BC. The major drawbacks of existing drugs …
have been approved by FDA for the treatment of BC. The major drawbacks of existing drugs …
[HTML][HTML] Synthesis, molecular structure and urease inhibitory activity of novel bis-Schiff bases of benzyl phenyl ketone: A combined theoretical and experimental …
Background Urease belongs to the family of amid hydrolases with two nickel atoms in their
core structure. On the basis of literature survey, this research work is mainly focused on the …
core structure. On the basis of literature survey, this research work is mainly focused on the …
Synthetic Transformation of 2-{2-Fluoro[1,1′-biphenyl]-4-yl} Propanoic Acid into Hydrazide–Hydrazone Derivatives: In Vitro Urease Inhibition and In Silico Study
In the present study, 28 acyl hydrazones (4–31) of flurbiprofen were synthesized in good to
excellent yield by reacting different aromatic aldehydes with the commercially available drug …
excellent yield by reacting different aromatic aldehydes with the commercially available drug …
Benzenesulfonohydrazides inhibiting urease: Design, synthesis, their in vitro and in silico studies
Keeping in view the therapeutic importance of ureases due to its involvement in different
pathological conditions, its inhibition was investigated by newly synthesized …
pathological conditions, its inhibition was investigated by newly synthesized …
Synthesis and evaluation of 1, 3, 5-triaryl-2-pyrazoline derivatives as potent dual inhibitors of urease and α-glucosidase together with their cytotoxic, molecular …
In the present work, a concise library of 1, 3, 5-triaryl-2-pyrazolines (2a–2q) was designed
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
HPLC-DAD phenolic profiles, antibiofilm, anti-quorum sensing and enzyme inhibitory potentials of Camellia sinensis (L.) O. Kuntze and Curcuma longa L.
This study aimed at investigating phenolic composition, anti-quorum sensing and enzyme
inhibitory potential of Camellia sinensis and Curcuma longa. HPLC-DAD identified and …
inhibitory potential of Camellia sinensis and Curcuma longa. HPLC-DAD identified and …
The potency of heterocyclic curcumin analogues: An evidence-based review
Curcumin, a potent phytochemical, has been a significant lead compound and has been
extensively investigated for its multiple bioactivities. Owing to its natural origin, non-toxic …
extensively investigated for its multiple bioactivities. Owing to its natural origin, non-toxic …
Curcumin nanoparticles: physicochemical fabrication, characterization, antioxidant, enzyme inhibition, molecular docking and simulation studies
Curcumin is an extensively studied natural compound due to its extensive biological
applications. However, there are some drawbacks linked to this compound such as poor …
applications. However, there are some drawbacks linked to this compound such as poor …
Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New N′-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors
Background: Hydrazides play a vital role in making biologically active compounds in various
fields of chemistry. These determine antioxidant, antidepressant, antimalarial, anti …
fields of chemistry. These determine antioxidant, antidepressant, antimalarial, anti …