Guanidines are fascinating small nitrogen-rich organic compounds, which have been
frequently associated with a wide range of biological activities. This is mainly due to their …

Kirenol, a potential natural diterpenoid molecule, is mainly found in Sigesbeckia species.
Kirenol has received a lot of interest in recent years due to its wide range of pharmacological …

Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

A concise total synthesis of the complex guanidinium toxin KB343 is reported traversing
through an unusual sequence of chemoselective transformations and strategic skeletal …

Sponges are among the earliest lineages of metazoans, with first fossil records dated back
to 890 million years ago. All sponge species present associations with microorganisms to …

Until now, relatively little is known about marine-derived fungal polysaccharides and their
activities. Exopolysaccharide AVP141-A was isolated from the broth of marine-derived …

Control of self-assembly is significant to the preparation of supramolecular materials, but the
control of hydration, responsiveness, dimension, catalysis of macrocyclic amphiphiles in an …

Bacteria of the genus Massilia represent an underexplored source of bioactive natural
products. Here, we report the discovery of massinidine (1), a guanidine alkaloid with …

Antimicrobial peptides (AMPs) often display guanidinium functionalities, and hence robust
synthetic procedures are needed to facilitate access to analogues with unnatural …

Isopropoxy benzene guanidine (IBG) is a guanidine derivative with antibacterial activity
against multidrug-resistant bacteria. A few studies have revealed the metabolism of IBG in …