Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

TA Yap, N Daver, M Mahendra, J Zhang… - Nature medicine, 2023 - nature.com
Although targeting oxidative phosphorylation (OXPHOS) is a rational anticancer strategy,
clinical benefit with OXPHOS inhibitors has yet to be achieved. Here we advanced IACS …

Neurological manifestations of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: report from the Consensus Conference on …

O Grauer, D Wolff, H Bertz, H Greinix, JS Kühl… - Brain, 2010 - academic.oup.com
A major obstacle of allogeneic haematopoietic stem cell transplantation is graft-versus-host
disease, an immune-mediated disorder that affects multiple tissues and organs with varying …

Neurocognitive dysfunction in hematopoietic cell transplant recipients: expert review from the late effects and Quality of Life Working Committee of the CIBMTR and …

D Buchbinder, DL Kelly, RF Duarte, JJ Auletta… - Bone marrow …, 2018 - nature.com
Hematopoietic cell transplantation (HCT) is a potentially curative treatment for children and
adults with malignant and non-malignant diseases. Despite increasing survival rates, long …

Neurologic complications of cancer and its treatment

P Giglio, MR Gilbert - Current oncology reports, 2010 - Springer
The central nervous system (CNS) and peripheral nervous system (PNS) are very
susceptible to cancer and its treatment. The most direct involvement of the nervous system …

[HTML][HTML] Neurologic complications after allogeneic hematopoietic stem cell transplantation

E Maffini, M Festuccia, L Brunello, M Boccadoro… - Biology of Blood and …, 2017 - Elsevier
Neurologic complications after hematopoietic stem cell transplantation are frequently life-
threatening, and their clinical management can be highly challenging. A wide spectrum of …

Posterior reversible encephalopathy syndrome in patients with cancer

S Singer, C Grommes, AS Reiner… - The …, 2015 - academic.oup.com
Background. Posterior reversible encephalopathy syndrome (PRES) is characterized by
neurologic symptoms with typical lesions on neuroimaging and may be associated with …

[HTML][HTML] Early and late neurological complications after reduced-intensity conditioning allogeneic stem cell transplantation

P Barba, JL Piñana, D Valcárcel, L Querol… - Biology of blood and …, 2009 - Elsevier
Neurological complications (NC) after allogeneic hematopoietic stem cell transplantation
(allo-HSCT) are common and life-threatening in most cases. They may involve either the …

Critically ill allogenic HSCT patients in the intensive care unit: a systematic review and meta-analysis of prognostic factors of mortality

C Saillard, M Darmon, M Bisbal, A Sannini… - Bone Marrow …, 2018 - nature.com
Outcome of patients undergoing allogenic hematopoietic stem cell transplantation (allo-
HSCT) has improved. To investigate if this improvement can be transposed to the ICU …

Neurologic complications after allogeneic hematopoietic stem cell transplantation: risk factors and impact

MR Dowling, S Li, BR Dey, SL McAfee… - Bone marrow …, 2018 - nature.com
Neurologic complications (NCs) may be a significant source of morbidity and mortality after
hematopoietic cell transplantation (HCT). We performed a retrospective study of 263 …

[HTML][HTML] Toxic leukoencephalopathy following fludarabine-associated hematopoietic cell transplantation

A Beitinjaneh, AM McKinney, Q Cao… - Biology of Blood and …, 2011 - Elsevier
Toxic leukoencephalopathy has been more thoroughly investigated during the last decade
because of the advance of magnetic resonance imaging (MRI) techniques. We analyzed …