The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L

A Ashraf, MU Ijaz, S Muzammil, MM Nazir, S Zafar… - Fitoterapia, 2023 - Elsevier
Since long, medicinal plants or herbs are being used in different traditional treatment
systems as therapeutic agents to treat a variety of illnesses. Bixa orellana L., an medicinal …

Therapeutic potential of bixin on inflammation: a mini review

S Shadisvaaran, KY Chin, S Mohd-Said… - Frontiers in Nutrition, 2023 - frontiersin.org
Chronic inflammation is the underlying mechanism for many diseases. Thus, inflammatory
signaling pathways are valuable targets for new treatment modalities. Natural products have …

Blackberry leaves as new functional food? Screening antioxidant, anti-inflammatory and microbiological activities in correlation with phytochemical analysis

M Paczkowska-Walendowska, A Gościniak… - Antioxidants, 2021 - mdpi.com
Blackberry fruits are recognized as functional foods while blackberry leaves are outside this
classification and they also contain active compounds with health-promoting potential …

Is Caperatic Acid the Only Compound Responsible for Activity of Lichen Platismatia glauca within the Nervous System?

E Studzińska-Sroka, A Majchrzak-Celińska… - Antioxidants, 2022 - mdpi.com
Lichens are a source of various biologically active compounds. However, the knowledge
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …

Bixin attenuates carbon tetrachloride induced oxidative stress, inflammation and fibrosis in kidney by regulating the Nrf2/TLR4/MyD88 and PPAR-γ/TGF-β1/Smad3 …

JQ Ma, YJ Zhang, ZK Tian, CM Liu - International immunopharmacology, 2021 - Elsevier
Bixin, an natural carotenoid extracted from the seeds of the Bixa orellana has been shown to
possess numerous important pharmacological activities. The present study was aimed to …

[HTML][HTML] Thymus fontanesii attenuates CCl4-induced oxidative stress and inflammation in mild liver fibrosis

EA Abdelghffar, WA Obaid, MO Alamoudi… - Biomedicine & …, 2022 - Elsevier
Liver injury is a major public health problem all over the world that raises the demand of
developing novel effective and safe remedies. Traditionally, Thyme (Thymus fontanesii) has …

Nrf2/HO-1 as a therapeutic target in renal fibrosis

EHM Hassanein, IM Ibrahim, EK Abd-Alhameed… - Life Sciences, 2023 - Elsevier
Chronic kidney disease (CKD) is one of the most prevalent chronic diseases and affects
between 10 and 14% of the world's population. The World Health Organization estimates …

[HTML][HTML] Evolution of the anticholinesterase, antioxidant, and anti-inflammatory activity of Epilobium angustifolium L. infusion during in vitro digestion

D Szwajgier, E Baranowska-Wójcik… - Journal of Functional …, 2021 - Elsevier
Fireweed (Epilobium angustifolium L.) has attracted attention due to its numerous biological
activities. In the present work, we produced a polyphenol-rich freeze-dried infusion …

Targeting NRF2 for improved skin barrier function and photoprotection: focus on the achiote-derived apocarotenoid bixin

M Rojo De La Vega, A Krajisnik, DD Zhang… - Nutrients, 2017 - mdpi.com
The transcription factor NRF2 (nuclear factor-E2-related factor 2) orchestrates major cellular
defense mechanisms including phase-II detoxification, inflammatory signaling, DNA repair …

Animal models of hepatotoxicity

GS Bhakuni, O Bedi, J Bariwal, R Deshmukh… - Inflammation …, 2016 - Springer
Introduction Liver is the largest and important organ in the body, involved in the metabolism
of food and drugs. Liver diseases are potentially life threatening for humans. The etiology of …