Glioblastoma remains the most common primary brain tumor after the age of 40 years.
Maximal safe surgery followed by adjuvant chemoradiotherapy has remained the standard …

Background and purpose: Despite the given advances in neuro-oncology most patients with
high grade malignant glioma ultimately fail locally or locoregionally. In parallel with …

In this paper, we present a fast and robust practical tool for segmentation of solid tumors with
minimal user interaction to assist clinicians and researchers in radiosurgery planning and …

PURPOSE: Patients with recurrent malignant gliomas treated with stereotactic radiosurgery
(SRS) and multiagent systemic therapies were reviewed to determine the effects of patient …

We evaluated the efficacy and safety of gamma knife stereotactic radiosurgery (GKSR)
followed by bevacizumab combined with chemotherapy in 11 patients with recurrent …

Background High-grade gliomas (HGG) comprise the most common primary adult brain
cancers and universally recur. Combination of re-irradiation therapy (reRT) and …

PURPOSE: Reirradiation is a treatment option for recurrent high-grade glioma with proven
but limited effectiveness. Therapies directed against vascular endothelial growth factor have …

BACKGROUND: The value of maximal safe cytoreductive surgery in recurrent high-grade
gliomas (HGGs) is gaining wider acceptance. However, patients may harbor recurrent …

OBJECTIVE: To review the authors' experience with Gamma Knife radiosurgery (GKR) for
small recurrent high-grade gliomas (HGGs) following prior radical resection, external-beam …

Malignant gliomas relapse in close proximity to the resection site, which is the
postoperatively irradiated volume. Studies on re-irradiation of glioma were examined …