Recent advances in lung-on-a-chip technology for modeling respiratory disease

JA Tavares-Negrete, P Das, S Najafikhoshnoo… - Bio-Design and …, 2023 - Springer
Tissue engineering approaches, including those to functional lung tissues, are finely honed
by the inclusion of upgraded devices that mimic biophysical and biochemical features in …

[HTML][HTML] Sex differences in neuroimmunoendocrine communication. Involvement on longevity

LM Suarez, E Diaz-Del Cerro, J Felix… - Mechanisms of ageing …, 2023 - Elsevier
Endocrine, nervous, and immune systems work coordinately to maintain the global
homeostasis of the organism. They show sex differences in their functions that, in turn …

[HTML][HTML] Lifestyle, course of COVID-19, and risk of Long-COVID in non-hospitalized patients

M Pływaczewska-Jakubowska, M Chudzik… - Frontiers in …, 2022 - frontiersin.org
Introduction The coronavirus disease (COVID) 2019 pandemic remains a great challenge for
the healthcare system. The widely reported prolonged signs and symptoms resulting from …

[HTML][HTML] Sex-specific outcomes in cancer therapy: the central role of hormones

P Bakhshi, JQ Ho, S Zanganeh - Frontiers in Medical Technology, 2024 - frontiersin.org
Sex hormones play a pivotal role in modulating various physiological processes, with
emerging evidence underscoring their influence on cancer progression and treatment …

Androgen receptor, a possible anti-infective therapy target and a potent immune respondent in SARS-CoV-2 spike binding: a computational approach

A Ahmad, Z Makhmutova, W Cao, S Majaz… - Expert Review of Anti …, 2023 - Taylor & Francis
Background Although androgen in gender disparity of COVID-19 has been implied, no direct
link has been provided. Research design and methods Here, we applied AlphaFold …

[HTML][HTML] Neutrophil heterogeneity and aging: implications for COVID-19 and wound healing

Y Liu, C Xiang, Z Que, C Li, W Wang, L Yin… - Frontiers in …, 2023 - frontiersin.org
Neutrophils play a critical role in the immune response to infection and tissue injury.
However, recent studies have shown that neutrophils are a heterogeneous population with …

Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 …

X Li, Y Zhou, S Yuan, X Zhou, L Wang, J Sun, L Yu… - elife, 2022 - elifesciences.org
Background: Epidemiological studies observed gender differences in COVID-19 outcomes,
however, whether sex hormone plays a causal in COVID-19 risk remains unclear. This study …

[HTML][HTML] Predictors of high SARS-CoV-2 immunoglobulin G titers in COVID-19 convalescent whole-blood donors: a cross-sectional study in China

J Tang, H Liu, Q Wang, X Gu, J Wang, W Li… - Frontiers in …, 2023 - frontiersin.org
Background Demographic information has been shown to help predict high antibody titers of
COVID-19 convalescent plasma (CCP) in CCP donors. However, there is no research on the …

An in-vivo-mimicking 3D lung cancer-on-a-chip model to study the effect of external stimulus on the progress and inhibition of cancer metastasis

P Das, S Najafikhoshnoo, JA Tavares-Negrete, Q Yi… - Bioprinting, 2022 - Elsevier
Metastatic lung cancer is one of the leading causes of high mortality worldwide. Here, an in-
vivo mimicking 3D-lung-cancer-on-a-chip (IVM3DLCOC) model is introduced, developed …

[HTML][HTML] Tracking the evolution of anti-SARS-CoV-2 antibodies and long-term humoral immunity within 2 years after COVID-19 infection

M Movsisyan, N Truzyan, I Kasparova, A Chopikyan… - Scientific Reports, 2024 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that gave rise to
COVID-19 infection produced a worldwide health crisis. The virus can cause a serious or …