Acute anterior uveitis (AAU) and the spondyloarthritis (SpA) subtypes ankylosing spondylitis,
reactive arthritis and psoriatic arthritis are among the inflammatory diseases affected by the …

The immune system has the power to modulate the expression of radiation-induced normal
and tumor tissue damage. On the one hand, it can contribute to cancer cure, and on the …

Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides (AAV) are
characterized by inflammation of small-to-medium-sized blood vessels and the presence of …

When we launched the Journal of Translational Medicine a few months ago, we were
interested primarily in exploring scientific consideration of this discipline. However, as …

Recent advances in the fields of immunology, genetics, molecular biology, bioinformatics,
and the Human Genome Project have allowed for the emergence of the field of vaccinomics …

Motivation Many biological processes are governed by protein–ligand interactions. One
such example is the recognition of self and non-self cells by the immune system. This …

Cytokines, small proteins (5-20kDa) required in cell signaling and as immunomodulating
agents in human body. Now, these cell signals are known to mediate many inflammatory …

Translational medicine is the integrated application of innovative pharmacology tools,
biomarkers, clinical methods, clinical technologies and study designs to improve disease …

The next 'golden age'in vaccinology will be ushered in by the new science of vaccinomics. In
turn, this will inform and allow the development of personalized vaccines, based on our …

Extensive clinical experience has shown that systemic interleukin (IL)-2 administration can
induce complete or partial regression of renal cell cancer (RCC) metastases in 15 to 20% of …