Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

Data normalization strategies for microRNA quantification

H Schwarzenbach, AM Da Silva, G Calin… - Clinical …, 2015 - academic.oup.com
BACKGROUND Different technologies, such as quantitative real-time PCR or microarrays,
have been developed to measure microRNA (miRNA) expression levels. Quantification of …

Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer

X Huang, T Yuan, M Liang, M Du, S Xia, R Dittmar… - European urology, 2015 - Elsevier
Abstract Background Extracellular microRNAs (miRNAs) embedded in circulating exosomes
may serves as prognostic biomarkers in cancer. Objective To identify and evaluate plasma …

miRNA in plasma exosome is stable under different storage conditions

Q Ge, Y Zhou, J Lu, Y Bai, X Xie, Z Lu - Molecules, 2014 - mdpi.com
Exosomes are small membrane-bound vesicles secreted by most cell types. Exosomes
contain various functional proteins, mRNAs and microRNAs (miRNAs) that could be used for …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

Plasma extracellular RNA profiles in healthy and cancer patients

T Yuan, X Huang, M Woodcock, M Du, R Dittmar… - Scientific reports, 2016 - nature.com
Extracellular vesicles are selectively enriched in RNA that has potential as disease
biomarkers. To systemically characterize circulating extracellular RNA (exRNA) profiles, we …

[HTML][HTML] MicroRNAs as non-invasive diagnostic biomarkers for gastric cancer: Current insights and future perspectives

A Link, J Kupcinskas - World Journal of Gastroenterology, 2018 - ncbi.nlm.nih.gov
Non-invasive diagnostic biomarkers may contribute to an early identification of gastric
cancer (GC) and improve the clinical management. Unfortunately, no sensitive and specific …

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

M Müller, HB Kuiperij, JA Claassen, B Küsters… - Neurobiology of …, 2014 - Elsevier
MicroRNAs (miRNAs) are small, noncoding RNAs that function in complex networks to
regulate protein expression. In the brain, they are involved in development and synaptic …

Highly effective and low-cost microRNA detection with CRISPR-Cas9

XY Qiu, LY Zhu, CS Zhu, JX Ma, T Hou… - ACS synthetic …, 2018 - ACS Publications
MicroRNAs have been reported as related to multiple diseases and have potential
applications in diagnosis and therapeutics. However, detection of miRNAs remains …

The expression and clinical significance of circulating microRNA-21 in serum of five solid tumors

B Wang, Q Zhang - Journal of cancer research and clinical oncology, 2012 - Springer
Abstract Purpose MicroRNA-21 (miR-21) was reported as being overexpressed in various
human cancerous tissues, but its expression in cancerous serum was not unanimous in …