For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …

Patients with type 2 diabetes mellitus (T2DM) are at high risk for macrovascular
complications, which represent the major cause of mortality. Despite effective treatment of …

Abstract Background The triglyceride glucose (TyG) index is an inexpensive clinical
surrogate marker for insulin resistance. However, the relationship between TyG index and …

Cardiovascular disease remains the principal cause of death and disability among patients
with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying …

A new cardiometabolic-based chronic disease (CMBCD) model is presented that provides a
basis for early and sustainable, evidence-based therapeutic targeting to promote …

Type 2 diabetes individuals are at high risk for macrovascular complications: myocardial
infarction, stroke and cardiovascular mortality. Recent cardiovascular outcome trials have …

Given the multi-faceted pathogenesis of atherosclerosis in type 2 diabetes mellitus (T2DM),
it is likely that interventions to mitigate this risk must address cardiovascular (CV) risk factors …

Insulin resistance is a hallmark of type 2 diabetes mellitus and is associated with a metabolic
and cardiovascular cluster of disorders (dyslipidaemia, hypertension, obesity [especially …

Abstract The Multi-Ethnic Study of Atherosclerosis was initiated in July 2000 to investigate
the prevalence, correlates, and progression of subclinical cardiovascular disease (CVD) in a …

OBJECTIVE: To evaluate whether the homeostasis model assessment (HOMA) is a reliable
surrogate measure of in vivo insulin sensitivity in humans. RESEARCH DESIGN AND …