Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress …

LJ Valotto Neto, M Reverete de Araujo… - Antioxidants, 2024 - mdpi.com
The aging of the global population has increased the prevalence of neurodegenerative
conditions. Bacopa monnieri (BM), an herb with active compounds, such as bacosides A …

Protein aggregation and neurodegenerative disease: structural outlook for the novel therapeutics

S Arar, MA Haque, R Kayed - Proteins: Structure, Function, and …, 2023 - Wiley Online Library
Before the controversial approval of humanized monoclonal antibody lecanemab, which
binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for …

Recent advancements in computational drug design algorithms through machine learning and optimization

S Choudhuri, M Yendluri, S Poddar, A Li… - Kinases and …, 2023 - mdpi.com
The goal of drug discovery is to uncover new molecules with specific chemical properties
that can be used to cure diseases. With the accessibility of machine learning techniques, the …

Identification of breast lesion through integrated study of gorilla troops optimization and rotation-based learning from MRI images

T Si, DK Patra, S Mallik, A Bandyopadhyay, A Sarkar… - Scientific Reports, 2023 - nature.com
Breast cancer has emerged as the most life-threatening disease among women around the
world. Early detection and treatment of breast cancer are thought to reduce the need for …

2D-QSAR, molecular docking and MD simulation based virtual screening of the herbal molecules against Alzheimer's disorder: an approach to predict CNS activity

A Thakur, B Sharma, A Parashar… - Journal of …, 2024 - Taylor & Francis
Acetylcholinesterase (AChE) is one of the key enzyme targets that have been used clinically
for the management of Alzheimer's Disorder (AD). Numerous reports in the literature predict …

Structural and molecular features of acetylcholinesterase targeting small molecules: leveraging in silico tools to combat Alzheimer's disease

A Haque, KM Alenezi, MSMA Rasheed - New Journal of Chemistry, 2024 - pubs.rsc.org
Alzheimer's disease (AD) is a progressive neurodegenerative condition that leads to the
gradual decline of neuronal cells. Despite significant interest and investment, complete …

[PDF][PDF] Abnormalities in EEG as Alzheimer Marker

S Ehteshamzad - J. Clin. Images Med. Case Rep, 2023 - jcimcr.org
Background Alzheimer's Disease (AD) is a neurodegenerative disorder that progresses
slowly and is the most common type of neurological disorder and dementia in the elderly [1 …

The Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review

LJV Neto, M Reverete, RCM Junior, NM Machado… - 2024 - preprints.org
The aging of the global population has increased the prevalence of neurodegenerative
conditions. Bacopa monnieri (BM), an herb with active compounds, such as bacosides A …

Unveiling Molecular Markers and Prediction of Stomach Cancer from Transcriptomic Profile: A Comprehensive Study of Feature Mining and Learning-based Algorithm

K Borah, HS Das, B Barua, S Chakraborty, A Li… - 2024 - researchsquare.com
RNA-Seq technology is one of the most authoritative technologies among all Next-
generation Sequencing technologies to produce the expression of transcripts in bulk and at …

[PDF][PDF] Computational Chemistry in Plant Biology: Unraveling the Molecular Basis of Plant-Drug Interactions and Biochemical Pathways

R Rehman, S Amjad, SAR Shah, N Ashfaq, I Saba… - researchgate.net
Computational chemistry plays a crucial role in advancing our understanding of plant
biology by unraveling the molecular basis of plant-drug interactions and biochemical …