Abstract The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des
Sciences Naturelles 1: 195–269, 1833) is a marine annelid that belongs to the Nereididae, a …

An old question about regeneration is whether it is an ancestral character which is a general
property of living matter, or whether it represents a set of specific adaptations to the different …

Animal bodies comprise diverse arrays of cells. To characterize cellular identities across an
entire body, we have compared the transcriptomes of single cells randomly picked from …

Background What impact gene loss has on the evolution of developmental processes, and
how function shuffling has affected retained genes driving essential biological processes …

The" Spiralia" represent one of the three major clades of bilaterian metazoans. Though
members of this clade exhibit tremendous diversity in terms of their larval and adult body …

Animal development is classified as conditional or autonomous based on whether cell fates
are specified through inductive signals or maternal determinants, respectively. Yet how …

Background: During gastrulation, endoderm and mesoderm are specified from a bipotential
precursor (endomesoderm) that is argued to be homologous across bilaterians. Spiralians …

Abstract Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase activated by
various types of collagens that performs a critical role in cell attachment, migration, survival …

Mesoderm represents the evolutionary youngest germ layer and forms numerous novel
tissues in bilaterian animals. Despite the established conservation of the gene regulatory …

Background Restorative regeneration, the capacity to reform a lost body part following
amputation or injury, is an important and still poorly understood process in animals …