[HTML][HTML] Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)

RV Thakker - Molecular and cellular endocrinology, 2014 - Elsevier
Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving
two or more endocrine glands within a single patient. Four major forms of MEN, which are …

Consensus: guidelines for diagnosis and therapy of MEN type 1 and type 2

ML Brandi, RF Gagel, A Angeli… - The Journal of …, 2001 - academic.oup.com
This is a consensus statement from an international group, mostly of clinical
endocrinologists. MEN1 and MEN2 are hereditary cancer syndromes. The commonest …

[图书][B] Pathology and genetics of tumours of endocrine organs

RA DeLellis - 2004 - books.google.com
This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the
endocrine pancreas, and inherited tumor syndromes. Each entity is extensively discussed …

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

MC Lemos, RV Thakker - Human mutation, 2008 - Wiley Online Library
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder
characterized by the occurrence of tumors of the parathyroids, pancreas, and anterior …

[HTML][HTML] MEN4 and CDKN1B mutations: the latest of the MEN syndromes

R Alrezk, F Hannah-Shmouni… - Endocrine-related …, 2017 - erc.bioscientifica.com
Multiple endocrine neoplasia (MEN) refers to a group of autosomal dominant disorders with
generally high penetrance that lead to the development of a wide spectrum of endocrine and …

Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study

B Vergès, F Boureille, P Goudet, A Murat… - The Journal of …, 2002 - academic.oup.com
To date, data on pituitary adenomas in MEN type 1 (MEN1) still have to be evaluated. We
analyzed the data of a large series of 324 MEN1 patients from a French and Belgian …

Menin: a scaffold protein that controls gene expression and cell signaling

S Matkar, A Thiel, X Hua - Trends in biochemical sciences, 2013 - cell.com
The protein menin is encoded by the MEN1 gene, which is mutated in patients with multiple
endocrine neoplasia type 1 (MEN1) syndrome. Although menin acts as a tumor suppressor …

Risk factors and causes of death in MEN1 disease. A GTE (Groupe d'Etude des Tumeurs Endocrines) cohort study among 758 patients

P Goudet, A Murat, C Binquet, C Cardot-Bauters… - World journal of …, 2010 - Springer
Background The natural history of multiple endocrine neoplasia type 1 (MEN1) is known
through single-institution or single-family studies. We aimed to analyze the risk factors and …

[HTML][HTML] Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

SK Agarwal, SC Guru, C Heppner, MR Erdos… - Cell, 1999 - cell.com
MEN1 is a tumor suppressor gene that encodes a 610 amino acid nuclear protein (menin) of
previously unknown function. Using a yeast two-hybrid screen with menin as the bait, we …

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

JS Crabtree, PC Scacheri, JM Ward… - Proceedings of the …, 2001 - National Acad Sciences
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant cancer syndrome,
characterized primarily by multiple tumors in the parathyroid glands, endocrine pancreas …