Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

The importance of breast adipose tissue in breast cancer

C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose
tissue is generally linked to excessive body fat, and it is well known that the female breast is …

Cancer-associated adipocytes: emerging supporters in breast cancer

C Zhao, M Wu, N Zeng, M Xiong, W Hu, W Lv… - Journal of Experimental …, 2020 - Springer
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis
and recurrence rate, and adipocytes are the largest components in breast tissue. The …

Investigation of the association between the fecal microbiota and breast cancer in postmenopausal women: a population-based case-control pilot study

JJ Goedert, G Jones, X Hua, X Xu, G Yu… - Journal of the …, 2015 - academic.oup.com
We investigated whether the gut microbiota differed in 48 postmenopausal breast cancer
case patients, pretreatment, vs 48 control patients. Microbiota profiles in fecal DNA were …

Adipocyte biology in breast cancer: From silent bystander to active facilitator

J Choi, YJ Cha, JS Koo - Progress in lipid research, 2018 - Elsevier
Adipocytes account for the largest proportion among the cells that comprise breast tissue;
therefore, they are considered to be a critical cell type in the tumor microenvironment of …

Chronic inflammation towards cancer incidence: A systematic review and meta-analysis of epidemiological studies

N Michels, C van Aart, J Morisse, A Mullee… - Critical Reviews in …, 2021 - Elsevier
This systematic review and meta-analysis provides epidemiological data on the relationship
between chronic inflammation, as measured by inflammatory blood parameters, and cancer …

Effect of high-intensity interval training on body composition and inflammatory markers in obese postmenopausal women: a randomized controlled trial

PRP Nunes, FM Martins, AP Souza, MAS Carneiro… - Menopause, 2019 - journals.lww.com
Objectives: This study tested whether high-intensity interval training is a time-efficient
strategy for improving visceral adiposity tissue and inflammatory markers in obese …

[HTML][HTML] The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance

MN Duong, A Geneste, F Fallone, X Li, C Dumontet… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Growing evidence has raised the important roles of adipocytes as an active player in the
tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells …

How the association between obesity and inflammation may lead to insulin resistance and cancer

MN Amin, MS Hussain, MS Sarwar… - Diabetes & Metabolic …, 2019 - Elsevier
Background and objectives Obesity is associated with metabolic dysfunction and over
nutrition. Increased body mass index and obesity are strongly amalgamated with changes in …

Obesity and breast cancer–Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue

C Gerard, KA Brown - Molecular and cellular endocrinology, 2018 - Elsevier
One in eight women will develop breast cancer over their lifetime making it the most
common female cancer. The cause of breast cancer is multifactorial and includes hormonal …