[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
[HTML][HTML] Role of microRNAs in translation regulation and cancer
S Oliveto, M Mancino, N Manfrini… - World journal of biological …, 2017 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …
They function by modulating transcriptional and translational programs and therefore they …
miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype
In atherosclerosis, resident vascular smooth muscle cells (VSMCs) in the blood vessels
become highly plastic and undergo phenotypic switching from the quiescent, contractile …
become highly plastic and undergo phenotypic switching from the quiescent, contractile …
Tumor suppressor miRNA-204-5p regulates growth, metastasis, and immune microenvironment remodeling in breast cancer
Various miRNAs play critical roles in the development and progression of solid tumors. In
this study, we describe the role of miR-204-5p in limiting growth and progression of breast …
this study, we describe the role of miR-204-5p in limiting growth and progression of breast …
[HTML][HTML] MicroRNAs: new players in the pathobiology of preeclampsia
KR Bounds, VL Chiasson, LJ Pan, S Gupta… - Frontiers in …, 2017 - frontiersin.org
Our understanding of how microRNAs (miRNAs) regulate gene networks and affect different
molecular pathways leading to various human pathologies has significantly improved over …
molecular pathways leading to various human pathologies has significantly improved over …
[HTML][HTML] The MSC-EV-microRNAome: a perspective on therapeutic mechanisms of action in sepsis and ARDS
Mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) have
emerged as innovative therapeutic agents for the treatment of sepsis and acute respiratory …
emerged as innovative therapeutic agents for the treatment of sepsis and acute respiratory …
Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs
Abstract SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
The role of microvesicles and its active molecules in regulating cellular biology
YM Lv, J Tan, Y Miao, Q Zhang - Journal of Cellular and …, 2019 - Wiley Online Library
Cell‐derived microvesicles are membrane vesicles produced by the outward budding of the
plasma membrane and released by almost all types of cells. These have been considered …
plasma membrane and released by almost all types of cells. These have been considered …
[HTML][HTML] miR-208a in cardiac hypertrophy and remodeling
XH Huang, JL Li, XY Li, SX Wang, ZH Jiao… - Frontiers in …, 2021 - frontiersin.org
Various stresses, including pressure overload and myocardial stretch, can trigger cardiac
remodeling and result in heart diseases. The disorders are associated with high risk of …
remodeling and result in heart diseases. The disorders are associated with high risk of …
Mechanisms of microRNAs in atherosclerosis
A Schober, C Weber - Annual Review of Pathology: Mechanisms …, 2016 - annualreviews.org
The maladaptation of endothelial cells to disturbed flow at arterial bifurcations increases
permeability for lipoproteins. Additional injury by chemically modified lipoproteins disrupts …
permeability for lipoproteins. Additional injury by chemically modified lipoproteins disrupts …