One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections

BX Wang, DSC Butler, M Hamblin… - Current opinion in …, 2023 - Elsevier
Highlights•Salmonella enterica is comprised of non-typhoidal and typhoidal
serovars.•Typhoidal Salmonella causes enteric fever instead of self-limiting …

Typhoid and paratyphoid fever: a clinical seminar

A Manesh, E Meltzer, C Jin, C Britto… - Journal of Travel …, 2021 - academic.oup.com
Rationale for review: Enteric fever (EF) caused by Salmonella enterica subspecies enterica
serovar Typhi (Salmonella Typhi) and S. Paratyphi (Salmonella Paratyphi) remains an …

WITHDRAWN: Detection of human genetic variation in VAC14 gene by ARMA-PCR technique and relation with typhoid fever infection in patients with gallbladder …

ZK Hanan, MB Saleh, EH Mezal, AT Jalil - 2021 - Elsevier
Withdrawal Notice WITHDRAWN: Detection of human genetic variation in VAC14 gene by
ARMA-PCR technique and relation with typhoid fever infection in patients with gallbladder …

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

Nature communications, 2019 - nature.com
The human genetic factors that affect resistance to infectious disease are poorly understood.
Here we report a genome-wide association study in 17,000 severe malaria cases and …

[HTML][HTML] Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine

MJ McFadden, ABR McIntyre, H Mourelatos, NS Abell… - Cell reports, 2021 - cell.com
Type I interferons (IFNs) induce hundreds of IFN-stimulated genes (ISGs) in response to viral
infection. Induction of these ISGs must be regulated for an efficient and controlled antiviral …

Revisiting Persistent Salmonella Infection and the Carrier State: What Do We Know?

N Foster, Y Tang, A Berchieri, S Geng, X Jiao, P Barrow - Pathogens, 2021 - mdpi.com
One characteristic of the few Salmonella enterica serovars that produce typhoid-like
infections is that disease-free persistent infection can occur for months or years in a small …

Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10

SL Jaslow, KD Gibbs, WF Fricke, L Wang, KJ Pittman… - Cell reports, 2018 - cell.com
Salmonella enterica is an important foodborne pathogen that uses secreted effector proteins
to manipulate host pathways to facilitate survival and dissemination. Different S. enterica …

American academy of optometry microbial keratitis think tank

LB Szczotka-Flynn, JP Shovlin… - Optometry and Vision …, 2021 - journals.lww.com
PURPOSE The American Academy of Optometry (AAO) gathered researchers and key
opinion leaders from around the world to discuss contact lens–associated microbial keratitis …

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection

ATY Yeung, YH Choi, AHY Lee, C Hale, H Ponstingl… - MBio, 2019 - Am Soc Microbiol
ABSTRACT A genome-scale CRISPR knockout library screen of THP-1 human
macrophages was performed to identify loss-of-function mutations conferring resistance to …

An atlas of genetic variation linking pathogen-induced cellular traits to human disease

L Wang, KJ Pittman, JR Barker, RE Salinas… - Cell host & …, 2018 - cell.com
Pathogens have been a strong driving force for natural selection. Therefore, understanding
how human genetic differences impact infection-related cellular traits can mechanistically …