Demystifying the CXCR4 conundrum in cancer biology: Beyond the surface signaling paradigm
The oncogenic chemokine duo CXCR4-CXCL12/SDF-1 (CXC Receptor 4-CXC Ligand
12/Stromal-derived factor 1) has been the topic of intense scientific disquisitions since Muller …
12/Stromal-derived factor 1) has been the topic of intense scientific disquisitions since Muller …
Development and Therapeutic Perspectives of CXCR4 Antagonists for Disease Therapy
J Yang, E Tian, L Chen, Z Liu, Y Ren, W Mao… - European Journal of …, 2024 - Elsevier
Abstract Chemokine receptor 4 (CXCR4) is a subtype receptor protein of the GPCR family
with a seven-transmembrane structure widely distributed in human tissues. CXCR4 is …
with a seven-transmembrane structure widely distributed in human tissues. CXCR4 is …
Scale-Up Preparation of Best-In-Class Orally Bioavailable CXCR4 Antagonist EMU-116 in an Academic Setting
CXCR4 is a seven-transmembrane chemokine receptor that is intimately involved in stem
cell niche maintenance and immune cell trafficking. Among several other pathophysiological …
cell niche maintenance and immune cell trafficking. Among several other pathophysiological …
Carbon-coated Cu nanoparticles as heterogeneous catalysts for cycloaddition of propargylamine to cyclic ketones
D Yehorov, S Sotnik, V Asaula, O Pariiska, E Senchylo… - 2023 - chemrxiv.org
A set of 22 composites was prepared by pyrolysis of Cu2+ complexes with phenanthroline
and 1, 2-diaminobenzene, deposited on SiO2 (Aerosil). All composites contained Cu and …
and 1, 2-diaminobenzene, deposited on SiO2 (Aerosil). All composites contained Cu and …