Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders

JM Middeldorp, AATP Brink, AJC Van den Brule… - Critical reviews in …, 2003 - Elsevier
Epstein–Barr virus (EBV) is associated with a still growing spectrum of clinical disorders,
ranging from acute and chronic inflammatory diseases to lymphoid and epithelial …

[PDF][PDF] Epstein-Barr virus (EBV) and its associated human cancers–genetics, epigenetics, pathobiology and novel therapeutics

Q Tao, LS Young, CB Woodman, PG Murray - Front Biosci, 2006 - researchgate.net
Introduction 3. Genetics of EBV 3.1. Genome structure 3.2. EBV strain variations 4. EBV
primary infection and persistence 4.1. In vitro models of EBV infection 4.2. EBV persistence …

Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein.

S Imai, S Koizumi, M Sugiura… - Proceedings of the …, 1994 - National Acad Sciences
In 1000 primary gastric carcinomas, 70 (7.0%) contained Epstein-Barr virus (EBV) genomic
sequences detected by PCR and Southern blots. The positive tumors comprised 8 of 9 …

[HTML][HTML] The association of Epstein–Barr virus with smooth-muscle tumors occurring after organ transplantation

ES Lee, J Locker, M Nalesnik, J Reyes… - … England Journal of …, 1995 - Mass Medical Soc
Background Epstein–Barr virus (EBV) has been associated with nasopharyngeal carcinoma,
some lymphomas, and lymphoproliferative disease after organ transplantation. Many …

Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells.

EM Deacon, G Pallesen, G Niedobitek… - The Journal of …, 1993 - rupress.org
Epstein-Barr virus (EBV) is associated with a number of different human tumors and appears
to play different pathogenetic roles in each case. Thus, immunoblastic B cell lymphomas of …

Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier state

RJ Tierney, N Steven, LS Young… - Journal of virology, 1994 - Am Soc Microbiol
Epstein-Barr virus (EBV) can display different forms of latent infection in B-cell lines in vitro;
however, the types of infection normally established by the virus in vivo remain largely …

Expression of Epstein‐Barr virus nuclear antigen‐1 induces B cell neoplasia in transgenic mice.

JB Wilson, JL Bell, AJ Levine - The EMBO journal, 1996 - embopress.org
The Epstein‐Barr virus (EBV) nuclear antigen‐1 (EBNA‐1) is a pleiotropic protein which has
been characterized extensively both biochemically and functionally. It is the only one of the …

Epstein–Barr virus–associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2

G Kelly, A Bell, A Rickinson - Nature medicine, 2002 - nature.com
Epstein–Barr virus (EBV) is etiologically linked to endemic Burkitt lymphoma (BL), but its
contribution to lymphomagenesis, versus that of the chromosomal translocation leading to c …

Ligation-anchored PCR: a simple amplification technique with single-sided specificity.

AB Troutt, MG McHeyzer-Williams… - Proceedings of the …, 1992 - National Acad Sciences
A simple, efficient, and sensitive technique has been developed for amplification of cDNAs
encoding molecules with 5'regions of unknown sequence. In this ligation-anchored PCR, T4 …

Transcriptional analysis of Epstein-Barr virus gene expression in EBV-positive gastric carcinoma: unique viral latency in the tumour cells

M Sugiura, S Imai, M Tokunaga, S Koizumi… - British journal of …, 1996 - nature.com
Although case-oriented evidence for an association of Epstein-Barr virus (EBV) with gastric
carcinoma has been accumulating recently, the interaction (s) between EBV and gastric …