Nicotinic acetylcholine, serotonin type 3, γ-amminobutyric acid type A, and glycine receptors
are major players of human neuronal communication. They belong to the family of …

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different
CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy …

The glycine receptor chloride channel (GlyR) is a member of the nicotinic acetylcholine
receptor family of ligand-gated ion channels. Functional receptors of this family comprise five …

γ‐Aminobutyric acid (GABA) emerged as a potentially important brain chemical just over 50
years ago, but its significance as a neurotransmitter was not fully realized until over 16 years …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Neurotransmission is the basis of neuronal communication and is critical for normal brain
development, behavior, learning, and memory. Exposure to drugs and chemicals can alter …

Strychnine‐sensitive glycine receptors (GlyRs) are known to mediate synaptic inhibition in
spinal cord, brainstem and other regions of the CNS. During the past 5 years, considerable …

The mechanisms that induce Alzheimer's disease (AD) are largely unknown thereby
deterring the development of disease-modifying therapies. One working hypothesis of AD is …

Gouty arthritis evokes joint pain and inflammation. Mechanisms driving gout pain and
inflammation remain incompletely understood. Here we show that CXCL5 activates CXCR2 …