The endothelium is a highly metabolically active organ that is involved in many physiological
processes, including the control of vasomotor tone, barrier function, leukocyte adhesion and …

The endothelium is a highly dynamic cell layer that is involved in a multitude of physiologic
functions, including the control of vasomotor tone, the trafficking of cells and nutrients, the …

Summary Dendritic cells (DCs), monocytes, and macrophages are leukocytes with critical
roles in immunity and tolerance. The DC network is evolutionarily conserved; the homologs …

The oral mucosa is a barrier site constantly exposed to rich and diverse commensal
microbial communities, yet little is known of the immune cell network maintaining immune …

Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-
lipoxygenase). The immediate product of 5-LO is LTA4 (leukotriene A4), which is …

Endothelial cell heterogeneity : Critical Care Medicine Endothelial cell heterogeneity : Critical
Care Medicine SCCM Pediatric Critical Care Medicine Critical Care Explorations Log in or …

The mercapturic acid pathway is a major route for the biotransformation of xenobiotic and
endobiotic electrophilic compounds and their metabolites. Mercapturic acids (N-acetyl-l …

γ-Glutamyl transpeptidase (GGT) catalyzes the transfer of the glutamyl moiety from
glutathione, and glutathione S-conjugates to acceptors to form another amide or to water to …

It is becoming increasingly accepted that macrophages play a crucial role in many diseases
associated with chronic inflammation, including atherosclerosis, obesity, diabetes, cancer …

Change in the intracellular concentration of osmolytes or the extracellular tonicity results in a
rapid transmembrane water flow in mammalian cells until intracellular and extracellular …