Bone morphogenic protein and mesenchymal stem cells to regenerate bone in calvarial defects: a systematic review
Background: The use of bone morphogenic protein and mesenchymal stem cells has shown
promise in promoting bone regeneration in calvarial defects. However, a systematic review …
promise in promoting bone regeneration in calvarial defects. However, a systematic review …
Coacervation‐Mediated Cytocompatible Formation of Supramolecular Hydrogels with Self‐Evolving Macropores for 3D Multicellular Spheroid Culture
Coacervation driven liquid–liquid phase separation of biopolymers has aroused
considerable attention for diverse applications, especially for the construction of …
considerable attention for diverse applications, especially for the construction of …
Stem cells and bone tissue engineering
Segmental bone defects that are caused by trauma, infection, tumor resection, or
osteoporotic fractures present significant surgical treatment challenges. Host bone autograft …
osteoporotic fractures present significant surgical treatment challenges. Host bone autograft …
Wnt10b regulates osteogenesis of adipose‐derived stem cells through Wnt/β‐catenin signalling pathway in osteoporosis
K Huang, S Cai, T Fu, Q Zhu, L Liu, Z Yao… - Cell …, 2024 - Wiley Online Library
Our previous finding revealed that the Wnt10b RNA expression of osteoporotic adipose‐
derived stem cells (OP‐ASCs) with impaired osteogenic capacity was significantly reduced …
derived stem cells (OP‐ASCs) with impaired osteogenic capacity was significantly reduced …
Mineral coated microparticles doped with fluoride and complexed with mRNA prolong transfection in fracture healing
Introduction: Impaired fracture healing, specifically non-union, has been found to occur up to
14% in tibial shaft fractures. The current standard of care to treat non-union often requires …
14% in tibial shaft fractures. The current standard of care to treat non-union often requires …
Effects of Control Factors on Protein–Polyelectrolyte Complex Coacervation
J Zhou, Y Wan, MA Cohen Stuart, M Wang… - …, 2023 - ACS Publications
Protein–polyelectrolyte complex coacervation is of particular interest for mimicking
intracellular phase separation and organization. Yet, the challenge arises from regulating …
intracellular phase separation and organization. Yet, the challenge arises from regulating …
Two-dimensional Nb2C-based nanoplatform augmented sonodynamic antibacterial therapy and bone regeneration
L Ma, X Zhang, H Wang, X Feng, J Lei, Y He… - Science China …, 2023 - Springer
Rapid disinfection and promotion of bone regeneration are two crucial aspects of the clinical
treatment of osteomyelitis. There is an urgent need to develop highly efficient bioactive …
treatment of osteomyelitis. There is an urgent need to develop highly efficient bioactive …
Dual-phase blocks for regeneration of critical-sized bone defects
Repair of critical-size bone defects (CBD) remains a challenge in orthopedic surgery due to
the restricted regenerative capacity of bone tissue. Herein, multi-functional biphasic calcium …
the restricted regenerative capacity of bone tissue. Herein, multi-functional biphasic calcium …
[HTML][HTML] β-catenin mRNA encapsulated in SM-102 lipid nanoparticles enhances bone formation in a murine tibia fracture repair model
Fractures continue to be a global economic burden as there are currently no osteoanabolic
drugs approved to accelerate fracture healing. In this study, we aimed to develop an …
drugs approved to accelerate fracture healing. In this study, we aimed to develop an …
MRL/MpJ mice resist to age-related and long-term ovariectomy-induced bone loss: implications for bone regeneration and repair
Osteoporosis and age-related bone loss increase bone fracture risk and impair bone
healing. The need for identifying new factors to prevent or treat bone loss is critical …
healing. The need for identifying new factors to prevent or treat bone loss is critical …