The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

METHODS We have conducted a series of systematic reviews on the efficacy of therapy in
IBS and CIC. There have been several systematic reviews of therapy for IBS and CIC …

Functional gastrointestinal disorders (FGIDs), the most common diagnoses in
gastroenterology, are recognized by morphologic and physiological abnormalities that often …

Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …

Dietary fibers/probiotics may relieve constipation via optimizing gut microbiome, yet with
limited trial-based evidences. We aimed to evaluate the effects of formulas with dietary fibers …

Abstract Purpose of Review The purpose of the review was to provide an update of the
Rome IV criteria for colorectal disorders with implications for clinical practice. Recent …

Introduction Chronic constipation is a common disorder with a reported prevalence ranging
from 3% to 27% in the general population. Several management strategies, including …

Functional constipation (FC), a condition characterized by heterogeneous symptoms
(infrequent bowel movements, hard stools, excessive straining, or a sense of incomplete …

Background: Functional constipation is a prevalent, burdensome gastrointestinal disorder
whose treatment remains challenging. Probiotics have been increasingly investigated in its …

Background & Aims In fecal samples from patients with chronic constipation, the microbiota
differs from that of healthy subjects. However, the profiles of fecal microbiota only partially …