Precision diagnostics is one of the two pillars of precision medicine. Sequencing efforts in
the past decade have firmly established cancer as a primarily genetically driven disease …

Purpose: Ibrutinib is a first-in-class inhibitor of Bruton tyrosine kinase. We previously
reported the safety and short-term antitumor activity of ibrutinib in 20 patients with relapsed …

Genetic testing has become widespread in daily medical care for gastrointestinal (GI)
cancers. However, unlike breast cancer and non-small cell lung cancer, in which …

Background Glioblastoma is the most common malignant primary brain tumour in adults and
driven by various genomic alterations. Next generation sequencing (NGS) provides timely …

Introduction Glioblastomas are aggressive primary intracranial tumours of the central
nervous system causing significant mortality and morbidity worldwide. Objective This study …

Objectives Describe an augmented intelligence approach to facilitate the update of evidence
for associations in knowledge graphs. Methods New publications are filtered through …

Simple Summary Glioblastoma (GBM) remains a disease with poor survival and limited
treatment options. The purpose of this retrospective study was to determine if routine …

目的筛选敲减哺乳动物雷帕霉素靶蛋白(mTOR) 基因后胶质瘤细胞表达上调的基因及信号通路,
探讨联合阻断mTOR 信号通路及其旁路激活通路抑制胶质瘤细胞生长的有效性. 方法选取5 …

Abstract Nations in Eastern and Southern Africa collectively reported> 23 million cases of
COVID-19 from 2020 until 2023. The case numbers are, however, likely to be widely …

Genomic testing is a critical component of precision medicine. It has influenced many
aspects of patient care, including diagnosis, disease monitoring, and treatment choice …