A2 milk: New perspectives for food technology and human health

S Fernández-Rico, AC Mondragón… - Foods, 2022 - mdpi.com
Although milk consumption is increasing worldwide, in some geographical regions, its
consumption has persistently declined in recent decades. This fact, together with the …

Health-related outcomes of genetic polymorphism of bovine β-casein variants: A systematic review of randomised controlled trials

D Daniloski, NMD Cunha, NA McCarthy… - Trends in Food Science …, 2021 - Elsevier
Background A number of randomised in vivo trials have to date investigated the health
impacts of the genetic variants A1 and A2 of bovine β-casein. The primary difference …

Milk containing A2 β-casein only, as a single meal, causes fewer symptoms of lactose intolerance than milk containing A1 and A2 β-caseins in subjects with lactose …

M Ramakrishnan, TK Eaton, OM Sermet, DA Savaiano - Nutrients, 2020 - mdpi.com
Acute-feeding and multiple-day studies have demonstrated that milk containing A2 β-casein
only causes fewer symptoms of lactose intolerance (LI) than milk containing both A1 and A2 …

[HTML][HTML] Worldwide research on the health effects of bovine milk containing A1 and A2 β-casein: Unraveling the current scenario and future trends through …

JA Gonzales-Malca, VA Tirado-Kulieva… - Current Research in …, 2023 - Elsevier
The possible adverse effect of consuming bovine milk with A1 β-casein (but not with A2 β-
casein) on health aspects due to the release of β-casomorphin-7 (BCM-7) is currently under …

Health implication of lactose intolerance and updates on its dietary management

A Li, J Zheng, X Han, Z Jiang, B Yang, S Yang… - International Dairy …, 2023 - Elsevier
Lactose intolerance is a gastrointestinal symptom caused by a deficiency or decreased
activity of the enzyme lactase in the gut, which makes it difficult to fully digest lactose in …

Difficulties in Establishing the Adverse Effects of β-Casomorphin-7 Released from β-Casein Variants—A Review

ML de Vasconcelos, LMFS Oliveira, JP Hill, AMC Vidal - Foods, 2023 - mdpi.com
β-Casomorphin-7 (BCM-7) is a peptide released through the proteolysis of β-casein (β-CN),
which is considered a bioactive peptide displaying evidence of promoting the binding and …

Casomorphins and gliadorphins have diverse systemic effects spanning gut, brain and internal organs

KB Woodford - International journal of environmental research and …, 2021 - mdpi.com
Food-derived opioid peptides include digestive products derived from cereal and dairy diets.
If these opioid peptides breach the intestinal barrier, typically linked to permeability and …

BCM-7: Opioid-like Peptide with Potential Role in Disease Mechanisms

E Bolat, F Eker, S Yılmaz, S Karav, E Oz, C Brennan… - Molecules, 2024 - mdpi.com
Bovine milk is an essential supplement due to its rich energy-and nutrient-rich qualities.
Caseins constitute the vast majority of the proteins in milk. Among these, β-casein comprises …

Bovine milk with variant β-casein types on immunological mediated intestinal changes and gut health of mice

B Liu, W Qiao, M Zhang, Y Liu, J Zhao, L Chen - Frontiers in Nutrition, 2022 - frontiersin.org
Dietary proteins provide bioactive peptides, which are important for host gastrointestinal
functions. We hypothesized that A2-type β-casein could provide gastrointestinal benefits and …

[HTML][HTML] What is the impact of amino acid mutations in the primary structure of caseins on the composition and functionality of milk and dairy products?

D Daniloski, NA McCarthy, T Huppertz… - Current Research in Food …, 2022 - Elsevier
The impact of amino acid mutations within the peptide structure of bovine milk protein is
important to understand as it can effect processability and subsequently effect its …