Nrf2 for protection against oxidant generation and mitochondrial damage in cardiac injury
QM Chen - Free Radical Biology and Medicine, 2022 - Elsevier
Myocardial infarction is the most common form of acute coronary syndrome. Blockage of a
coronary artery due to blood clotting leads to ischemia and subsequent cell death in the form …
coronary artery due to blood clotting leads to ischemia and subsequent cell death in the form …
[HTML][HTML] Innate-adaptive immunity interplay and redox regulation in immune response
Innate and adaptive immune cell activation and infiltration is the key characteristic of tissue
inflammation. The innate immune system is the front line of host defense in which innate …
inflammation. The innate immune system is the front line of host defense in which innate …
MAFG-driven astrocytes promote CNS inflammation
Multiple sclerosis is a chronic inflammatory disease of the CNS. Astrocytes contribute to the
pathogenesis of multiple sclerosis, but little is known about the heterogeneity of astrocytes …
pathogenesis of multiple sclerosis, but little is known about the heterogeneity of astrocytes …
New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury
As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …
increased prevalence and incidence. In addition to its macrovascular damage, through its …
Nrf2 and oxidative stress in liver ischemia/reperfusion injury
R G. Bardallo, A Panisello‐Roselló… - The FEBS …, 2022 - Wiley Online Library
In response to stress signal, nuclear factor‐erythroid 2‐related factor 2 (Nrf2) induces the
expression of target genes involved in antioxidant defense and detoxification. Nrf2 activity is …
expression of target genes involved in antioxidant defense and detoxification. Nrf2 activity is …
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms
D Ezhilarasan - Toxicology, 2021 - Elsevier
Methotrexate (MTX) is one of the most effective and widely used drugs in the management of
autoimmune and dermatological diseases. Rheumatoid arthritis and psoriasis patients who …
autoimmune and dermatological diseases. Rheumatoid arthritis and psoriasis patients who …
Food protein-derived antioxidant peptides: Molecular mechanism, stability and bioavailability
Y Zhu, F Lao, X Pan, J Wu - Biomolecules, 2022 - mdpi.com
The antioxidant activity of protein-derived peptides was one of the first to be revealed among
the more than 50 known peptide bioactivities to date. The exploitation value associated with …
the more than 50 known peptide bioactivities to date. The exploitation value associated with …
Arbutin as a skin depigmenting agent with antimelanogenic and antioxidant properties
YC Boo - Antioxidants, 2021 - mdpi.com
Arbutin is a compound of hydroquinone and D-glucose, and it has been over 30 years since
there have been serious studies on the skin lightening action of this substance. In the …
there have been serious studies on the skin lightening action of this substance. In the …
[HTML][HTML] Mitochondria in cancer
D Grasso, LX Zampieri, T Capelôa, JA Van de Velde… - Cell stress, 2020 - ncbi.nlm.nih.gov
The rediscovery and reinterpretation of the Warburg effect in the year 2000 occulted for
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …