Presynaptic calcium channels: specialized control of synaptic neurotransmitter release
AC Dolphin, A Lee - Nature Reviews Neuroscience, 2020 - nature.com
Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …
specialized for the conversion of electrical impulses into the exocytotic release of …
The role of Cdk5 in Alzheimer's disease
SL Liu, C Wang, T Jiang, L Tan, A Xing, JT Yu - Molecular neurobiology, 2016 - Springer
Alzheimer's disease (AD) is known as the most fatal chronic neurodegenerative disease in
adults along with progressive loss of memory and other cognitive function disorders. Cyclin …
adults along with progressive loss of memory and other cognitive function disorders. Cyclin …
Presynaptic spike timing-dependent long-term depression in the mouse hippocampus
Y Andrade-Talavera, P Duque-Feria, O Paulsen… - Cerebral …, 2016 - academic.oup.com
Spike timing-dependent plasticity (STDP) is a Hebbian learning rule important for synaptic
refinement during development and for learning and memory in the adult. Given the …
refinement during development and for learning and memory in the adult. Given the …
Mechanisms of endocannabinoid control of synaptic plasticity
BL Winters, CW Vaughan - Neuropharmacology, 2021 - Elsevier
The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …
A review on cyclin-dependent kinase 5: An emerging drug target for neurodegenerative diseases
Abstract Cyclin-dependent kinase 5 (CDK5) is the serine/threonine-directed kinase mainly
found in the brain and plays a significant role in developing the central nervous system …
found in the brain and plays a significant role in developing the central nervous system …
C dk5 regulates multiple cellular events in neural development, function and disease
T Kawauchi - Development, growth & differentiation, 2014 - Wiley Online Library
Cyclin‐dependent kinases (CDK s) generally regulate cell proliferation in dividing cells,
including neural progenitors. In contrast, an unconventional CDK, C dk5, is predominantly …
including neural progenitors. In contrast, an unconventional CDK, C dk5, is predominantly …
Cdk5-dependent phosphorylation of CaV3. 2 T-type channels: possible role in nerve ligation-induced neuropathic allodynia and the compound action potential in …
K Gomez, A Calderón-Rivera, A Sandoval… - Journal of …, 2020 - Soc Neuroscience
Voltage-gated T-type Ca2+ (CaV3) channels regulate diverse physiological events,
including neuronal excitability, and have been linked to several pathological conditions such …
including neuronal excitability, and have been linked to several pathological conditions such …
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice
MV Rao, MK McBrayer, J Campbell… - Journal of …, 2014 - Soc Neuroscience
Tau pathogenicity in Alzheimer9s disease and other tauopathies is thought to involve the
generation of hyperphosphorylated, truncated, and oligomeric tau species with enhanced …
generation of hyperphosphorylated, truncated, and oligomeric tau species with enhanced …
Molecular machines regulating the release probability of synaptic vesicles at the active zone
C Körber, T Kuner - Frontiers in synaptic neuroscience, 2016 - frontiersin.org
The fusion of synaptic vesicles (SVs) with the plasma membrane of the active zone (AZ)
upon arrival of an action potential (AP) at the presynaptic compartment is a tightly regulated …
upon arrival of an action potential (AP) at the presynaptic compartment is a tightly regulated …