RNA metabolism plays a central role in cell growth. It is essential to regulate RNA synthesis,
processing, stability and degradation. Conformational changes in RNA are key elements in …

In eukaryotic organisms, the orthologs of the DEAD-box RNA helicase Ded1p from yeast
and DDX3 from human form a well-defined subfamily that is characterized by high sequence …

Planarians are known for their strong regenerative ability. This ability has been considered
to reside in the totipotent somatic stem cell called the “neoblast.” Neoblasts contain a unique …

The vasa gene is essential for germline formation in Drosophila. Vasa-related genes have
been isolated from several organisms including nematode, frog and mammals. In order to …

Localization of maternal mRNAs in many developing organisms provides the basis for both
initial polarity during oogenesis and patterning during embryogenesis. Prominent examples …

ABSTRACT mRNAs concentrated in specific regions of the oocyte have been found to
encode determinants that specify cell fate. We show that an intermediate filament fraction …

The vasa (vas)-related genes are members of the DEAD box protein family and are involved
in germ cell formation in higher metazoans. In the present study, we cloned the vas-related …

Several studies have implicated hepatitis C virus (HCV) core in influencing the expression of
host genes. To identify cellular factors with a possible role in HCV replication and …

RNA helicases represent a large family of proteins that have been detected in almost all
biological systems where RNA plays a central role. They are ubiquitously distributed over a …

CRM1 is an export receptor mediating rapid nuclear exit of proteins and RNAs to the
cytoplasm. CRM1 export cargoes include proteins with a leucine-rich nuclear export signal …