Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Although nanopores can be used for single-molecule sequencing of nucleic acids using low-
cost portable devices, the characterization of proteins and their modifications has yet to be …

Mass spectrometry (MS) is increasingly being used to probe the structure and dynamics of
proteins and the complexes they form with other macromolecules. There are now several …

Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

Glycosylated proteins account for a majority of the posttranslation modifications of cell
surface, secreted, and circulating proteins. Within the tumor microenvironment, the presence …

Introduction: For decades, the role of glycans and glycoproteins in the progression of breast
cancer and other cancers have been evaluated. Through extensive studies focused on …

Protein glycosylation is ubiquitous in biological systems and plays essential roles in many
cellular events. Global and site‐specific analysis of glycoproteins in complex biological …

Protein glycosylation, an important PTM, plays an essential role in a wide range of biological
processes such as immune response, intercellular signaling, inflammation, and host …

Cancer early detection and treatment response prediction continue to pose significant
challenges. Cancer liquid biopsies focusing on detecting circulating tumor cells (CTCs) and …