Deep learning for autosegmentation for radiotherapy treatment planning: State-of-the-art and novel perspectives

AC Erdur, D Rusche, D Scholz, J Kiechle… - Strahlentherapie und …, 2024 - Springer
The rapid development of artificial intelligence (AI) has gained importance, with many tools
already entering our daily lives. The medical field of radiation oncology is also subject to this …

Personalized predictions of Glioblastoma infiltration: Mathematical models, Physics-Informed Neural Networks and multimodal scans

RZ Zhang, I Ezhov, M Balcerak, A Zhu, B Wiestler… - Medical Image …, 2025 - Elsevier
Predicting the infiltration of Glioblastoma (GBM) from medical MRI scans is crucial for
understanding tumor growth dynamics and designing personalized radiotherapy treatment …

Solving inverse problems in physics by optimizing a discrete loss: Fast and accurate learning without neural networks

P Karnakov, S Litvinov, P Koumoutsakos - PNAS nexus, 2024 - academic.oup.com
In recent years, advances in computing hardware and computational methods have
prompted a wealth of activities for solving inverse problems in physics. These problems are …

Diffusion tensor transformation for personalizing target volumes in radiation therapy

G Buti, A Ajdari, CP Bridge, GC Sharp, T Bortfeld - Medical Image Analysis, 2024 - Elsevier
Diffusion tensor imaging (DTI) is used in tumor growth models to provide information on the
infiltration pathways of tumor cells into the surrounding brain tissue. When a patient-specific …

A Learnable Prior Improves Inverse Tumor Growth Modeling

J Weidner, I Ezhov, M Balcerak, MC Metz… - arXiv preprint arXiv …, 2024 - arxiv.org
Biophysical modeling, particularly involving partial differential equations (PDEs), offers
significant potential for tailoring disease treatment protocols to individual patients. However …

A novel, finite-element-based framework for sparse data solution reconstruction and multiple choices

W Bielajewa, M Baxter, P Nithiarasu - arXiv preprint arXiv:2410.06386, 2024 - arxiv.org
Digital twinning offers a capability of effective real-time monitoring and control, which are
vital for cost-intensive experimental facilities, particularly the ones where extreme conditions …

Spatial Brain Tumor Concentration Estimation for Individualized Radiotherapy Planning

J Weidner, M Balcerak, I Ezhov, A Datchev… - arXiv preprint arXiv …, 2024 - arxiv.org
Biophysical modeling of brain tumors has emerged as a promising strategy for personalizing
radiotherapy planning by estimating the otherwise hidden distribution of tumor cells within …

BILO: BILEVEL LOCAL OPERATOR LEARNING FOR

PDE INVERSE - openreview.net
We propose a new neural network based method for solving inverse problems for partial
differential equations (PDEs) by formulating the PDE inverse problem as a bilevel …