Circular RNA: A promising new star for the diagnosis and treatment of colorectal cancer

S Zhang, J Sun, M Gu, G Wang, X Wang - Cancer medicine, 2021 - Wiley Online Library
Background Colorectal cancer (CRC) is one of the most common malignant tumors of the
digestive tract. According to the research of circular RNAs in the CRC field, compared with …

Transgelins: cytoskeletal associated proteins implicated in the metastasis of colorectal cancer

J Liu, Y Zhang, Q Li, Y Wang - Frontiers in cell and developmental …, 2020 - frontiersin.org
Transgelins, including transgelin-1 (T-1), transgelin-2 (T-2), and transgelin-3 (T-3), are a
family of actin-binding proteins (ABPs) that can alter the structure and morphology of the …

Late‐life plasma proteins associated with prevalent and incident frailty: A proteomic analysis

F Liu, TR Austin, JA Schrack, J Chen, J Walston… - Aging …, 2023 - Wiley Online Library
Proteomic approaches have unique advantages in the identification of biological pathways
that influence physical frailty, a multifactorial geriatric syndrome predictive of adverse health …

The Antioxidant and In Vitro Wound Healing Activity of Cotyledon orbiculata Aqueous Extract and the Synthesized Biogenic Silver Nanoparticles

C Tyavambiza, M Meyer, AD Wusu… - International Journal of …, 2022 - mdpi.com
The synthesis of silver nanoparticles using biogenic methods, particularly plants, has led to
the discovery of several effective nanoparticles. In many instances, plant-derived silver …

Inhibition of EphA3 expression in tumour stromal cells suppresses tumour growth and progression

ME Vail, RH Farnsworth, L Hii, S Allen, S Arora… - Cancers, 2023 - mdpi.com
Simple Summary We have identified the cell guidance receptor EphA3 on distinct
stromal/fibroblast-like cell types in the tumour microenvironment (TME) that promote growth …

Palladium (II) complexes of substituted salicylaldehydes: Synthesis, characterization and investigation of their biological profile

A Zianna, G Geromichalos, AM Fiotaki… - Pharmaceuticals, 2022 - mdpi.com
Five palladium (II) complexes of substituted salicylaldehydes (X-saloH, X= 4-Et2N (for 1), 3,
5-diBr (for 2), 3, 5-diCl (for 3), 5-F (for 4) or 4-OMe (for 5)) bearing the general formula [Pd (X …

Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release

C Sun, K Zhang, C Ni, J Wan, X Duan, X Lou, X Yao… - Oncogenesis, 2023 - nature.com
Abstract Cancer-associated fibroblasts (CAFs), the principal constituent of the heterogenous
tumor microenvironment, have been shown to promote tumor progression; however, the …

Therapeutic targeting of the TPX2/TTK network in colorectal cancer

H Shaath, R Vishnubalaji, R Elango… - Cell Communication and …, 2023 - Springer
Background While the increased screening, changes in lifestyle, and recent advances in
treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease …

[HTML][HTML] Proteomics-based identification of proteins in tumor-derived exosomes as candidate biomarkers for colorectal cancer

DY Zhao, TF Yin, QQ Wang, YC Zhou… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Colorectal cancer (CRC) is the second leading cause of cancer-related
death, with high morbidity worldwide. There is an urgent need to find reliable diagnostic …

Evolution and function of calponin and transgelin

TB Hsieh, JP Jin - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Calponin and transgelin (originally named SM22) are homologous cytoskeleton proteins
that regulate actin-activated myosin motor functions in smooth muscle contraction and non …