Mesenchymal stem cells (MSCs) have recently made significant progress with multiple
clinical trials targeting modulation of immune responses, regeneration of bone, cartilage …

Given the limited spontaneous repair that follows cartilage injury, demand is growing for
tissue engineering approaches for cartilage regeneration. There are two major applications …

Achieving a high cell density of animal cells is a prerequisite for different medical
applications such as cell therapy, tissue engineering, and vaccine production. Microcarrier …

Microcarrier cell culture systems provide an attractive alternative to the conventional
monolayer cell culture for cell amplification, due to their high surface area-to-volume ratio …

Articular cartilage is composed of superficial, medial, and deep zones, which endow the
tissue with biphasic mechanical properties to withstand shearing force and compressional …

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering,
in which the chondrocytes represent the most commonly used cell type. Since research in …

Background aims Cartilage tissue engineering with human mesenchymal stromal cells
(hMSC) is promising for allogeneic cell therapy. To achieve large-scale hMSC propagation …

Dermal fibroblasts play a pivotal role in cell therapy, serving as versatile cells essential for
tissue repair and regeneration. Their unique ability to produce extracellular matrix …

Stimuli-sensitive or smart polymers are a most important class of soft materials which
transiently adapt their physical and/or chemical properties upon small changes in the …

The growth of CP5 chondrocytes on microcarriers beads in a disposable bioreactor under
various conditions of wave-assisted agitation has been compared and discussed. Influences …