Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by a
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …

Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …

Mitochondria are best known as the sites for production of respiratory ATP and are essential
for eukaryotic life. They have their own genome but the great majority of the mitochondrial …

Cadmium, a heavy metal pollutant in industrial production, is found in air, water and soil,
which is harmful to human health and can lead to diseases, such as asthma, lung cancer …

As a widely acknowledged environmental pollutant, lead (Pb) exhibits neurological toxicity
primarily due to the vulnerability of neural system. It is suggested that Pb could perturb …

Paraquat (methyl viologen), is a non-selective contact herbicide and well known
mitochondrial toxicant. Mitochondria are the center of cellular metabolism, and involved in …

Mercury is one of the 10 toxic chemicals with major public health concerns. Continuous
exposure to low levels of heavy metals including mercury is related to renal injury, especially …

Stroke is a devastating disease with high mortality and disability rates. Previous research
has established that mitochondria, as major regulators, are both influenced by stroke, and …

Changes in metabolic pathways are often associated with the development of various
pathologies including cancer, inflammatory diseases, obesity and metabolic syndrome …

Nowadays ambient particulate matter (PM) levels still regularly exceed the guideline values
established by World Health Organization in most urban areas. Numerous experimental …