Friedelin and 3β-friedelinol: pharmacological activities

MH Radi, RA El-Shiekh, AM El-Halawany… - Revista Brasileira de …, 2023 - Springer
The interest in herbal medicine as a source of drug leads is being reinforced, especially for
tackling challenging therapeutic areas such as antimicrobial resistance, cardiovascular …

Structural and catalytic insight into the unique pentacyclic triterpene synthase TwOSC

Y Luo, X Ma, Y Qiu, Y Lu, S Shen, Y Li… - Angewandte Chemie …, 2023 - Wiley Online Library
The oxidosqualene cyclase (OSC) catalyzed cyclization of the linear substrate (3S)‐2, 3‐
oxidosqualene to form diverse pentacyclic triterpenoid (PT) skeletons is one of the most …

Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene

TM Souza-Moreira, TB Alves, KA Pinheiro… - Scientific reports, 2016 - nature.com
Among the biologically active triterpenes, friedelin has the most-rearranged structure
produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In …

Synthesis and spectroscopic characterization of ternary copper (II) complexes containing nitrogen and oxygen donors as functional mimics of catechol oxidase and …

AEMM Ramadan, SY Shaban, MM Ibrahim… - New Journal of …, 2020 - pubs.rsc.org
Two ternary copper (II) complexes 1 [(Cu2Me4en) 4 (EDTA)] and 2 [(CuMe4en) 2 (MIDA)]
containing the mixed ligand system of 1, 1′, 4, 4′-tetramethylethylenediamine (Me4en)(L) …

Anionic ligands tune the structural and catalytic properties of quinoxaline-based copper (II) complexes as mimetics of copper-containing oxidase protein

AM Fathy, MM Hessien, MM Ibrahim… - Journal of Molecular …, 2022 - Elsevier
The hexadentate ligand containing quinoxaline backbone along with its Cu (II)-based
complexes with various anionic ligands were synthesized and their structures were …

Palladium (II) based imines; synthesis, characterization, X-ray structural analysis; DFT and catalytic hydrogenation study

MM Ibrahim, AM Fathy, SA Al-Harbi, SA Sallam… - Journal of …, 2021 - Elsevier
Based on the bridge alkyl chain length between the two azomethine linkages of the bis ortho
naphtholimine ligands, two synthetic techniques were used to prepare a novel series of …

Synthesis and structural characterization of pyridine-based Mn (III), Fe (III), and Co (III) complexes as SOD mimics and BSA binding studies

MM Ibrahim, MA El-Kemary, SA Al-Harbi… - Journal of Molecular …, 2021 - Elsevier
Abstract Interaction of 2-picolylamine (2-PA) with Mn (II), Fe (III) and Co (II) chlorides in an
ethanolic solution yields two types of metal chelates. The analytical data, thermal analysis …

Ternary complexes containing Copper (II), L-Valinate and α, ά-bipyridyl or 1, 10-phenanthroline: Synthesis, characterization, ligand substitution and oxidase …

AM Ramadan, SY Shaban, MM Ibrahim… - Journal of Molecular …, 2019 - Elsevier
Ternary copper (II) complexes with the molecular formulae of [Cu II LL′] X or [Cu II LL′ X];
L= l-Valinate; L′= α, ά-bipyridyl or 1, 10-phenanthroline and X is Cl¯, Br¯, NO 3¯, AcO¯ …

[HTML][HTML] Pentacyclic triterpenes from branches of Maytenus robusta and in vitro cytotoxic property against 4T1 cancer cells

GF Sousa, DCF Soares, WN Mussel… - Journal of the Brazilian …, 2014 - SciELO Brasil
Two new friedelane-type compounds 1 and 2 and five known pentacyclic triterpenes were
isolated from branches of Maytenus robusta. Their structures were identified as 3, 16-dioxo …

[HTML][HTML] Preliminary phytochemical study of the Ecuadorian plant Croton elegans Kunth (Euphorbiaceae)

C Herrera, Y Pérez, V Morocho, C Armijos… - Journal of the Chilean …, 2018 - SciELO Chile
ABSTRACT The species Croton elegans Kunth, belonging to the family Euphorbiaceae and
known with the common name “mosquera”, is a native medicinal plant of Ecuador. Due to its …