[HTML][HTML] Targeted strategy in lipid-lowering therapy

E Dayar, O Pechanova - Biomedicines, 2022 - mdpi.com
Dyslipidemia is characterized by a diminished lipid profile, including increased level of total
cholesterol and low-density lipoprotein cholesterol (LDL-c) and reduced level of high …

Pharmacokinetic aspects of nanoparticle-in-matrix drug delivery systems for oral/buccal delivery

RC Feitosa, DC Geraldes… - Frontiers in …, 2019 - frontiersin.org
Oral route maintains its predominance among the ones used for drug delivery, especially
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …

Wound healing efficacy of rosuvastatin transethosomal gel, I optimal optimization, histological and in vivo evaluation

RM Zaki, VD Seshadri, AS Mutayran, LA Elsawaf… - Pharmaceutics, 2022 - mdpi.com
This study aimed to make a formulation and statistical optimization of transethosomal
formulations of rosuvastatin (ROS) to enhance its topical wound healing efficiency. Design …

Spanlastics as an efficient delivery system for the enhancement of thymoquinone anticancer efficacy: Fabrication and cytotoxic studies against breast cancer cell lines

E Alaaeldin, M Mostafa, HF Mansour… - Journal of Drug Delivery …, 2021 - Elsevier
Thymoquinone (TQ), a pleiotropic compound isolated from the seeds of Nigella sativa has a
great potential as a chemotherapeutic agent against several cancers. However, its limited …

Brain targeting of resveratrol through intranasal lipid vesicles labelled with gold nanoparticles: in vivo evaluation and bioaccumulation investigation using computed …

HF Salem, RM Kharshoum, HA Abou-Taleb… - Journal of drug …, 2019 - Taylor & Francis
Resveratrol is a promising neuroprotective agent against neurodegenerative disorders such
as Alzheimer's disease. Resveratrol-loaded transferosomes and nanoemulsions were …

Self-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis

YX Dou, JT Zhou, TT Wang, YF Huang… - International journal …, 2018 - Taylor & Francis
Background Bruceine D (BD) is a major bioactive component isolated from the traditional
Chinese medicinal plant Brucea javanica which has been widely utilized to treat dysentery …

Rosuvastatin calcium-based novel nanocubic vesicles capped with silver nanoparticles-loaded hydrogel for wound healing management: Optimization employing Box …

HF Salem, MM Nafady, MGELD Ewees… - Journal of Liposome …, 2022 - Taylor & Francis
Chronic wounds are a serious problem that could cause severe morbidity and even death.
The ability of statins including rosuvastatin calcium (RVS) to enhance wound healing was …

A novel transdermal nanoethosomal gel of lercanidipine HCl for treatment of hypertension: optimization using Box-Benkhen design, in vitro and in vivo …

HF Salem, SF El-Menshawe, RA Khallaf… - Drug delivery and …, 2020 - Springer
Poor bioavailability of drugs via oral route is the greatest challenge facing drug formulation.
To overcome this obstacle, transdermal route was commonly used as an alternative route to …

[PDF][PDF] The efficacy of using different antibiotics to prevent maternal surgical site infections in covid-19-infected cases

A Zaki, MO Elgendy, MA Abdelrahman, HA Ali… - Eur. Chem …, 2023 - researchgate.net
Medical costs go up as a result of surgical site infections (SSIs). Women with COVID-19
infection are more susceptible to infection. Maxipime and Unictam have been evaluated to …

Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and …

N Akhtar, SAA Mohammed, RA Khan, M Yusuf… - Journal of Drug Delivery …, 2020 - Elsevier
The self-generating nano-emulsifying drug delivery system (SNEDDS) is among the most
effective approaches to enhance the oral bioavailability of a therapeutic agent, especially of …