The outcomes of children born to mothers with autoimmune rheumatic diseases

L Andreoli, J Andersen, T Avcin… - The Lancet …, 2024 - thelancet.com
Maternal autoimmune rheumatic diseases can influence the outcomes of children through
several life stages. During pregnancy, maternal inflammation and autoantibodies can hinder …

The time of equipoise on the use of biological DMARDs in for inflammatory arthritis during pregnancy is finally over: a reappraisal of evidence to optimise pregnancy …

I Giles, I Thorne, NS Schmidt, C Reid… - The Lancet …, 2024 - thelancet.com
Active inflammatory arthritis in pregnancy is associated with an increased risk of adverse
pregnancy outcomes. Treatment of active inflammation and maintenance of low disease …

[HTML][HTML] Infant ustekinumab clearance, risk of infection, and development after exposure during pregnancy

M Julsgaard, JW Wieringa, SMD Baunwall… - Clinical …, 2024 - Elsevier
Background Evidence on ustekinumab safety in pregnancy is gradually expanding, but its
clearance in the postnatal period is unknown. The aim of this study was to investigate …

Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation

OH Nielsen, JM Gubatan, KL Kolho, SE Streett… - The Lancet, 2024 - thelancet.com
Inflammatory bowel disease (IBD) affects reproductive planning due to psychological effects
and mechanical problems related to surgery. Children of people with IBD have an increased …

Vedolizumab and Ustekinumab Levels in Pregnant Women With Inflammatory Bowel Disease and Infants Exposed In Utero

R Prentice, E Flanagan, EK Wright, PR Gibson… - Clinical …, 2024 - Elsevier
Background & Aims Vedolizumab and ustekinumab pharmacokinetics in pregnancy and the
infant after in utero exposure remain incompletely defined. We aim to define the antenatal …

[HTML][HTML] Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment

L Wu, L Yang, X Qian, W Hu, S Wang… - Journal of Functional …, 2024 - mdpi.com
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as potential therapeutic strategies. A systematic review and analysis must be …

Safety of Rotavirus Vaccination in Infants That Were Exposed to Biologics In Utero: A Systematic Review

TL Schell, L Fass, ME Hitchcock… - Inflammatory Bowel …, 2024 - academic.oup.com
Background In infants that were exposed to biologics in utero, gastroenterology societal
guidelines have either recommended against administration of the live rotavirus vaccine …

[HTML][HTML] Live Rotavirus Vaccination Appears Low-risk in Infants Born to Mothers With Inflammatory Bowel Disease on Biologics

K Ernest-Suarez, LE Murguía-Favela… - Clinical …, 2024 - Elsevier
Background & Aims Biologic therapies in the context of inflammatory bowel disease and
pregnancy lead to improved maternal and fetal outcomes. Placental transfer results in …

[HTML][HTML] What Should We Know about Drug Levels and Therapeutic Drug Monitoring during Pregnancy and Breastfeeding in Inflammatory Bowel Disease under …

M Barrau, X Roblin, L Andromaque, A Rozieres… - Journal of Clinical …, 2023 - mdpi.com
Data on the real long-term influences of in utero drug exposure in pregnant women on
childhood development are scarce and remain not well determined and depend on the …

[HTML][HTML] Common Mistakes in Managing Patients with Inflammatory Bowel Disease

JP Gisbert, M Chaparro - Journal of Clinical Medicine, 2024 - mdpi.com
Introduction: Errors are very common in medical practice and in particular, in the healthcare
of patients with inflammatory bowel disease (IBD); however, most of these can be prevented …