The hepatic sinusoid harbors 4 different cells: endothelial cells (100, 101), Kupffer cells (96,
102, 103), fat-storing cells (34, 51, 93), and pit cells (14, 107. 108). Each cell type has its …

Although metastasis is the leading cause of cancer deaths, it is quite rare at the cellular
level. Only a rare subset of cancer cells (~ 1 in 1.5 billion) can complete the entire metastatic …

Recently we demonstrated that the nonadherent (to plastic) fraction of human PBMC could
be activated by IL-2 to inhibit Cryptococcus neoformans growth. Here we characterize the …

In adoptive immunotherapy (AIT) of cancer, lymphocytes are isolated from the patient's blood
and activated in vitro by the cytokine interleukin-2 (IL-2). In response to the IL-2 the …

Adherent lymphokine‐activated killer (A‐LAK) cells are purified IL‐2 activated natural killer
(NK) cells with potent anti‐tumor cytotoxic activity. They have been used in the adoptive …

The cellular immune response depends on the delivery of lymphocytes from the lymph node
to the peripheral site of antigenic challenge. During their passage through the inflammatory …

Cell invasion assays are important to obtain valuable functional data relating to tissue
migration and invasion of effector lymphocytes. Boyden chamber invasion assays represent …

An experimental set‐up for estimating a) cellular migration under agarose and b) response
to chemoattractant gradients built up in the agarose was used in order to explore the …

The possibility of using interleukin 2 (IL-2)-activated natural killer cells (A-NK) to carry
methoxymorpholinyl doxorubicin (MMDX; PNU 152243) to liver-infiltrating tumours was …

Natural killer (NK) cells are effector cells of the innate immune system that are responsible
for mediating cellular cytotoxicity against virally infected or neoplastically transformed cells …