Bacteriophages are obligate parasites of bacteria characterized by the breadth of hosts that
they can infect. This “host range” depends on the genotypes and morphologies of the phage …

For decades, biomedically centered studies of bacteria have focused on mechanistic drivers
of disease in their mammalian hosts. Likewise, molecular studies of bacteriophage have …

The evolution of antibiotic-resistant bacteria threatens to become the leading cause of
worldwide mortality. This crisis has renewed interest in the practice of phage therapy. Yet …

Interactions between species catalyze the evolution of multiscale ecological networks,
including both nested and modular elements that regulate the function of diverse …

Dormancy is an adaptation to living in fluctuating environments. It allows individuals to enter
a reversible state of reduced metabolic activity when challenged by unfavorable conditions …

The evolution and spread of antibiotic‐resistant bacteria have renewed interest in phage
therapy, the use of bacterial viruses (phages) to combat bacterial infections. The delivery of …

Bacteria often evolve resistance to phage through the loss or modification of cell surface
receptors. In Escherichia coli and phage λ, such resistance can catalyze a coevolutionary …

Characterizing how viruses evolve expands our understanding of the underlying
fundamental processes, such as mutation, selection and drift. One group of viruses whose …

Diverse viruses and their hosts are interconnected through complex networks of infection,
which are thought to influence ecological and evolutionary processes, but the principles …

The number of multidrug‐resistant strains of bacteria is increasing rapidly, while the number
of new antibiotic discoveries has stagnated. This trend has caused a surge in interest in …