Homocysteine–from disease biomarker to disease prevention
AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …
that are associated with raised concentrations of plasma total homocysteine. The …
[HTML][HTML] Implication of hyperhomocysteinemia in blood retinal barrier (BRB) dysfunction
Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has
been linked to different systemic and neurological diseases, well-known as a risk factor for …
been linked to different systemic and neurological diseases, well-known as a risk factor for …
Paraoxonase 1 and homocysteine metabolism
J Perła-Kaján, H Jakubowski - Amino acids, 2012 - Springer
Abstract Paraoxonase 1 (PON1), a component of high-density lipoprotein (HDL), is a
calcium-dependent multifunctional enzyme that connects metabolisms of lipoproteins and …
calcium-dependent multifunctional enzyme that connects metabolisms of lipoproteins and …
[HTML][HTML] Accurate image analysis of the retina using hessian matrix and binarisation of thresholded entropy with application of texture mapping
In this paper, we demonstrate a comprehensive method for segmenting the retinal
vasculature in camera images of the fundus. This is of interest in the area of diagnostics for …
vasculature in camera images of the fundus. This is of interest in the area of diagnostics for …
[HTML][HTML] Rebuilding microbiome for mitigating traumatic brain injury: importance of restructuring the gut-microbiome-brain axis
AK George, J Behera, RP Homme, N Tyagi… - Molecular …, 2021 - Springer
Traumatic brain injury (TBI) is a damage to the brain from an external force that results in
temporary or permanent impairment in brain functions. Unfortunately, not many treatment …
temporary or permanent impairment in brain functions. Unfortunately, not many treatment …
Homocysteine in ocular diseases
TA Ajith - Clinica Chimica Acta, 2015 - Elsevier
Homocysteine (Hcy) is a derived sulfur-containing and non-proteinogenic amino acid. The
metabolism of Hcy occurs either through the remethylation to methionine or transsulfuration …
metabolism of Hcy occurs either through the remethylation to methionine or transsulfuration …
Homocysteine and progression of generalized small-vessel disease: the SMART-MR Study
RP Kloppenborg, MI Geerlings, FL Visseren… - Neurology, 2014 - AAN Enterprises
Objectives: Assuming the involvement of homocysteine in a generalized small-vessel
disease, we investigated the association of homocysteine levels with progression of white …
disease, we investigated the association of homocysteine levels with progression of white …
[HTML][HTML] Hyperhomocysteinemia alters retinal endothelial cells barrier function and angiogenic potential via activation of oxidative stress
Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as
diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the …
diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the …
[HTML][HTML] Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors
HH Chang, DPC Lin, YS Chen, HJ Liu, W Lin… - Molecular …, 2011 - ncbi.nlm.nih.gov
Purpose Hyperhomocysteinemia is known to cause degeneration of retinal ganglion cells,
but its influence on photoreceptors remains largely unknown. In particular, the role of …
but its influence on photoreceptors remains largely unknown. In particular, the role of …
The influence of age and central foveal thickness on foveal zone size in healthy people
D Gong, X Zou, X Zhang, W Yu, Y Qu… - … Surgery, Lasers and …, 2016 - journals.healio.com
BACKGROUND AND OBJECTIVE: To investigate the influence of age and central foveal
thickness (CFT) on the foveal avascular zone (FAZ) size in healthy people using optical …
thickness (CFT) on the foveal avascular zone (FAZ) size in healthy people using optical …