Periodontitis: a multifaceted disease of tooth-supporting tissues

E Könönen, M Gursoy, UK Gursoy - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …

Application of chitosan in bone and dental engineering

A Aguilar, N Zein, E Harmouch, B Hafdi, F Bornert… - Molecules, 2019 - mdpi.com
Chitosan is a deacetylated polysaccharide from chitin, the natural biopolymer primarily
found in shells of marine crustaceans and fungi cell walls. Upon deacetylation, the …

Recent advances of chitosan-based injectable hydrogels for bone and dental tissue regeneration

G Tang, Z Tan, W Zeng, X Wang, C Shi, Y Liu… - … in Bioengineering and …, 2020 - frontiersin.org
Traditional strategies of bone repair include autografts, allografts and surgical
reconstructions, but they may bring about potential hazard of donor site morbidity, rejection …

[HTML][HTML] Immunomodulatory properties of dental tissue-derived mesenchymal stem cells: implication in disease and tissue regeneration

O Andrukhov, C Behm, A Blufstein… - World journal of stem …, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are considered as an attractive tool for tissue regeneration
and possess a strong immunomodulatory ability. Dental tissue-derived MSCs can be …

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration

J Liu, B Chen, J Bao, Y Zhang, L Lei, F Yan - Stem cell research & therapy, 2019 - Springer
Background The inflammation and regeneration process may be accompanied by the shift in
the M1/M2 polarization of macrophages to adapt to extracellular signals. How the …

Alloplastic bone substitutes for periodontal and bone regeneration in dentistry: Current status and prospects

S Fukuba, M Okada, K Nohara, T Iwata - Materials, 2021 - mdpi.com
Various bone graft products are commercially available worldwide. However, there is no
clear consensus regarding the appropriate bone graft products in different clinical situations …

Akkermansia muciniphila reduces Porphyromonas gingivalis‐induced inflammation and periodontal bone destruction

O Huck, H Mulhall, G Rubin, Z Kizelnik… - Journal of clinical …, 2020 - Wiley Online Library
Aim Akkermansia muciniphila is a beneficial gut commensal, whose anti‐inflammatory
properties have recently been demonstrated. This study aimed to evaluate the effect of A …

Pulp–dentin tissue healing response: a discussion of current biomedical approaches

D Shah, T Lynd, D Ho, J Chen, J Vines… - Journal of clinical …, 2020 - mdpi.com
Dental pulp tissue exposed to mechanical trauma or cariogenic process results in root canal
and/or periapical infections, and conventionally treated with root canal procedures. The …

Contribution of statins towards periodontal treatment: a review

C Petit, F Batool, IM Bugueno, P Schwinté… - Mediators of …, 2019 - Wiley Online Library
The pleiotropic effects of statins have been evaluated to assess their potential benefit in the
treatment of various inflammatory and immune‐mediated diseases including periodontitis …

Synthesis of a novel electrospun polycaprolactone scaffold functionalized with ibuprofen for periodontal regeneration: An in vitro andin vivo study

F Batool, DN Morand, L Thomas, IM Bugueno… - Materials, 2018 - mdpi.com
Ibuprofen (IBU) has been shown to improve periodontal treatment outcomes. The aim of this
study was to develop a new anti-inflammatory scaffold by functionalizing an electrospun …