Recent advances in colon drug delivery systems

R Arévalo-Pérez, C Maderuelo, JM Lanao - Journal of Controlled Release, 2020 - Elsevier
As a result of its ability to target certain drugs and/or peptides to the colonic region for the
treatment of several diseases while avoiding systemic absorption and potential side effects …

[HTML][HTML] Pharmaceutical application of tablet film coating

KS Seo, R Bajracharya, SH Lee, HK Han - Pharmaceutics, 2020 - mdpi.com
Tablet film coating is a common but critical process providing various functionalities to
tablets, thereby meeting diverse clinical needs and increasing the value of oral solid dosage …

[图书][B] Aqueous polymeric coatings for pharmaceutical dosage forms

LA Felton - 2016 - taylorfrancis.com
Aqueous-based film coating has become routine in the pharmaceutical industry. This
process eliminates the use of organic solvents and thus avoids economic, environmental …

Scale up of pan coating process using quality by design principles

AM Agrawal, P Pandey - Journal of pharmaceutical sciences, 2015 - Elsevier
Scale up of pan coating process is of high importance to the pharmaceutical and food
industry. The number of process variables and their interdependence in a pan coating …

Modeling the coating layer thickness in a pharmaceutical coating process

S Madlmeir, T Forgber, M Trogrlic, D Jajcevic… - European Journal of …, 2021 - Elsevier
Although mechanistic numerical simulations can offer great insights into a process, they are
limited with respect to resolved process time. While statistical models provide long-term …

Mechanical properties of polymeric films prepared from aqueous dispersions

LA Felton, PB O'Donnell… - … polymeric coatings for …, 2008 - taylorfrancis.com
Pharmaceutically acceptable polymers used in the film coating of solid dosage forms are
primarily based on acrylic or cellulosic polymers. Many of these polymers have been …

[HTML][HTML] Development of intestinal colonic drug delivery systems for diverticular disease: A QbD approach

R Arévalo-Pérez, C Maderuelo, JM Lanao - European Journal of …, 2024 - Elsevier
This study aimed to advance the development of intestinal colon-coated sustained-release
matrix tablets of metronidazole for diverticulitis treatment, employing the Quality by Design …

Design of experiments to study the impact of process parameters on droplet size and development of non-invasive imaging techniques in tablet coating

TJ Dennison, J Smith, MP Hofmann, CE Bland… - PLoS …, 2016 - journals.plos.org
Atomisation of an aqueous solution for tablet film coating is a complex process with multiple
factors determining droplet formation and properties. The importance of droplet size for an …

Understanding lethal mechanisms and preventive strategies in probiotic tablet production–a review

B Wang, A Middleton, R Gibson, J Khanolkar… - Powder Technology, 2024 - Elsevier
Probiotics are live microorganisms known for conferring health benefits through the
improvement or restoration of gut microbiota, and tablet is one of the commonly used forms …

A dynamic model of tablet film coating processes for control system design

CP Rodrigues, C Duchesne, É Poulin… - Computers & Chemical …, 2023 - Elsevier
Aqueous film coating is a common and important step in the production of most
pharmaceutical tablets. Controlling this process is beneficial to maintain stable and optimal …