Hundreds of millions of people are affected by hyperinsulinaemia, insulin resistance, obesity
and the dysglycaemia that mark a common progression from metabolic health to type 2 …

Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

The incidence of obesity which leads to insulin resistance (IR) and metabolic disorder is
increasing in developing countries, including Indonesia. Male adults have a higher risk of …

Background Elevation of serum ferritin levels is frequently observed in non-alcoholic fatty
liver disease (NAFLD) patients. Our study aims to examine the association between serum …

Context Hyperinsulinemia and adiposity are associated with one another, but the
directionality of this relation is debated. Objective Here, we tested the direction of the causal …

Environmentally induced or epigenetic-related beta-cell dysfunction and insulin resistance
play a critical role in the progression to diabetes. We developed a mathematical modeling …

Introduction. Obesity is a risk factor to develop metabolic syndrome (MetS) and type 2
diabetes mellitus (T2DM). Insulin resistance (IR) plays a major part in both. With increasing …

Background. Adiponectin acts to prevent vascular dysfunction due to obesity by inhibiting
ICAM‐1 and VCAM‐1 expressions. Objective. We investigate adiponectin ICAM‐1, VCAM‐1 …

Background Dietary fat has been suggested to be the cause of various health issues.
Obesity, hypertension, cardiovascular disease, diabetes, dyslipidemia, and kidney disease …

Background Obesity and its associated health conditions, type 2 diabetes mellitus (T2DM)
and nonalcoholic fatty liver disease (NAFLD), are worldwide health problems. It has been …